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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4S1
All Species:
47.58
Human Site:
Y20
Identified Species:
80.51
UniProt:
Q9Y587
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y587
NP_001121598.1
144
17005
Y20
Q
T
R
L
S
K
Y
Y
E
H
V
D
I
N
K
Chimpanzee
Pan troglodytes
XP_522814
159
18485
Y20
Q
T
R
L
S
K
Y
Y
E
H
V
D
I
N
K
Rhesus Macaque
Macaca mulatta
XP_001094284
157
18652
Y20
Q
T
Q
L
C
K
Y
Y
E
H
V
D
I
N
K
Dog
Lupus familis
XP_850275
144
16957
Y20
Q
T
R
L
S
K
Y
Y
E
H
V
E
I
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL1
144
16799
Y20
Q
T
R
L
S
K
Y
Y
E
H
V
D
I
N
K
Rat
Rattus norvegicus
P62744
142
16999
Y20
K
T
R
L
A
K
W
Y
M
Q
F
D
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512751
220
25891
Y96
Q
T
R
L
S
R
Y
Y
E
H
I
E
M
N
K
Chicken
Gallus gallus
XP_421226
144
17052
Y20
Q
T
R
L
S
R
Y
Y
E
H
I
E
I
H
K
Frog
Xenopus laevis
NP_001089698
144
16961
Y20
Q
T
R
L
S
R
Y
Y
E
R
T
E
V
Q
R
Zebra Danio
Brachydanio rerio
NP_001003826
140
16307
Y20
Q
T
R
L
S
K
Y
Y
E
A
V
D
L
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308286
143
16921
Y21
Q
T
R
L
A
Q
Y
Y
E
W
L
T
L
E
E
Maize
Zea mays
O50016
132
15996
Y20
K
T
R
L
A
K
Y
Y
V
P
L
E
D
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
Y22
K
I
R
L
K
K
W
Y
T
A
M
S
A
G
E
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
V21
T
R
L
A
K
W
Y
V
P
Y
S
D
E
E
K
Conservation
Percent
Protein Identity:
100
69.8
81.5
97.9
N.A.
95.8
43
N.A.
56.8
84.7
77.7
75
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
85.9
100
N.A.
97.9
66.6
N.A.
62.2
95.1
93.7
86.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
93.3
N.A.
100
40
N.A.
73.3
73.3
53.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
73.3
N.A.
100
100
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
55.5
38.1
N.A.
N.A.
37.8
42.3
Protein Similarity:
83.3
61.8
N.A.
N.A.
63.4
64.5
P-Site Identity:
46.6
40
N.A.
N.A.
26.6
20
P-Site Similarity:
80
80
N.A.
N.A.
53.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
22
0
0
0
0
15
0
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
50
15
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
72
0
0
36
8
15
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
15
0
43
0
0
% I
% Lys:
22
0
0
0
15
65
0
0
0
0
0
0
0
0
65
% K
% Leu:
0
0
8
93
0
0
0
0
0
0
15
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
72
0
8
0
0
8
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
8
86
0
0
22
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
0
0
0
58
0
0
0
0
0
8
8
0
8
0
% S
% Thr:
8
86
0
0
0
0
0
0
8
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
43
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
15
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
86
93
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _