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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD3
All Species:
29.39
Human Site:
S616
Identified Species:
58.79
UniProt:
Q9Y597
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y597
NP_057205.2
815
88984
S616
P
N
I
S
P
A
T
S
V
V
Q
H
S
H
L
Chimpanzee
Pan troglodytes
XP_514196
957
103885
A784
H
D
T
T
H
E
A
A
T
Y
G
S
M
R
P
Rhesus Macaque
Macaca mulatta
XP_001105750
815
89008
S616
P
N
I
S
P
A
T
S
V
V
Q
H
S
H
L
Dog
Lupus familis
XP_536118
789
86372
S591
P
N
I
S
P
A
T
S
V
V
Q
H
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFX3
815
88843
S617
P
N
I
S
P
A
T
S
V
L
Q
H
S
R
L
Rat
Rattus norvegicus
P0C5J9
704
75954
S533
S
T
G
Q
R
V
C
S
V
R
S
V
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510454
817
89351
S616
P
N
I
S
P
A
T
S
V
V
Q
H
S
R
L
Chicken
Gallus gallus
XP_419418
945
100884
S740
P
N
I
S
P
A
T
S
V
V
Q
P
N
R
L
Frog
Xenopus laevis
NP_001087426
806
88197
S611
P
N
I
S
P
A
T
S
V
V
H
Q
S
R
L
Zebra Danio
Brachydanio rerio
XP_697568
835
90893
S637
P
N
I
S
P
A
P
S
V
L
Q
H
S
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394892
690
76665
I519
K
I
V
S
L
E
A
I
E
S
C
I
S
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784158
652
71962
G481
Y
V
R
L
S
S
T
G
Q
R
V
C
L
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
99.5
93.9
N.A.
93.6
56.4
N.A.
88
66.6
81.2
74.1
N.A.
N.A.
52.3
N.A.
53.3
Protein Similarity:
100
82.1
99.5
94.8
N.A.
96.8
66.5
N.A.
92.2
72.5
87.2
82.6
N.A.
N.A.
64.2
N.A.
64.1
P-Site Identity:
100
0
100
93.3
N.A.
86.6
13.3
N.A.
93.3
80
80
80
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
13.3
N.A.
93.3
86.6
80
86.6
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
67
17
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
9
0
0
9
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
9
50
0
17
0
% H
% Ile:
0
9
67
0
0
0
0
9
0
0
0
9
0
9
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
9
0
0
0
0
17
0
0
9
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
67
0
0
0
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
67
0
0
0
67
0
9
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
9
0
59
9
0
0
0
% Q
% Arg:
0
0
9
0
9
0
0
0
0
17
0
0
0
59
9
% R
% Ser:
9
0
0
75
9
9
0
75
0
9
9
9
67
0
9
% S
% Thr:
0
9
9
9
0
0
67
0
9
0
0
0
0
0
0
% T
% Val:
0
9
9
0
0
9
0
0
75
50
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _