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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD3
All Species:
10.3
Human Site:
S742
Identified Species:
20.61
UniProt:
Q9Y597
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y597
NP_057205.2
815
88984
S742
F
S
E
S
K
K
R
S
S
E
D
E
N
E
N
Chimpanzee
Pan troglodytes
XP_514196
957
103885
K898
N
K
I
E
F
R
K
K
G
G
F
E
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001105750
815
89008
S742
F
S
E
S
K
K
R
S
S
E
D
E
N
E
N
Dog
Lupus familis
XP_536118
789
86372
S717
L
E
S
K
K
R
S
S
E
E
E
N
E
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFX3
815
88843
S743
L
S
E
P
K
K
R
S
A
E
D
E
N
E
H
Rat
Rattus norvegicus
P0C5J9
704
75954
S646
C
G
H
R
G
S
P
S
P
P
Q
A
G
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510454
817
89351
G744
S
S
D
A
K
K
R
G
S
E
E
E
Y
D
N
Chicken
Gallus gallus
XP_419418
945
100884
G872
S
L
D
P
K
R
R
G
P
E
E
E
G
E
A
Frog
Xenopus laevis
NP_001087426
806
88197
G736
K
K
R
V
G
E
D
G
T
E
S
K
S
E
L
Zebra Danio
Brachydanio rerio
XP_697568
835
90893
R762
S
P
G
D
Q
R
R
R
A
H
L
M
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394892
690
76665
P632
N
V
S
G
G
P
T
P
E
E
L
W
K
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784158
652
71962
R594
L
L
R
A
T
Q
L
R
A
S
S
T
T
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
99.5
93.9
N.A.
93.6
56.4
N.A.
88
66.6
81.2
74.1
N.A.
N.A.
52.3
N.A.
53.3
Protein Similarity:
100
82.1
99.5
94.8
N.A.
96.8
66.5
N.A.
92.2
72.5
87.2
82.6
N.A.
N.A.
64.2
N.A.
64.1
P-Site Identity:
100
6.6
100
20
N.A.
73.3
6.6
N.A.
53.3
33.3
13.3
13.3
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
20
100
33.3
N.A.
86.6
6.6
N.A.
80
53.3
40
33.3
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
25
0
0
9
0
9
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
0
9
0
0
0
25
0
0
9
0
% D
% Glu:
0
9
25
9
0
9
0
0
17
67
25
50
17
50
0
% E
% Phe:
17
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
9
9
25
0
0
25
9
9
0
0
25
9
17
% G
% His:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
17
0
9
50
34
9
9
0
0
0
9
9
0
9
% K
% Leu:
25
17
0
0
0
0
9
0
0
0
17
0
0
17
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
9
25
9
25
% N
% Pro:
0
9
0
17
0
9
9
9
17
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
17
9
0
34
50
17
0
0
0
0
0
0
17
% R
% Ser:
25
34
17
17
0
9
9
42
25
9
17
0
9
0
0
% S
% Thr:
0
0
0
0
9
0
9
0
9
0
0
9
9
0
0
% T
% Val:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _