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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDF2
All Species:
9.09
Human Site:
S508
Identified Species:
22.22
UniProt:
Q9Y5A9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5A9
NP_057342.2
579
62334
S508
F
V
K
D
V
P
N
S
Q
L
R
H
I
R
L
Chimpanzee
Pan troglodytes
XP_525419
559
60896
L494
N
Q
L
R
H
I
R
L
E
N
N
D
N
K
P
Rhesus Macaque
Macaca mulatta
XP_001086120
559
60922
L494
N
Q
L
R
H
I
R
L
E
N
N
D
N
K
P
Dog
Lupus familis
XP_535336
712
76490
S641
F
V
K
D
V
P
N
S
Q
L
R
H
I
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P59326
559
60860
R493
N
N
Q
L
R
H
I
R
L
E
N
N
D
N
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506380
561
61309
L496
N
Q
L
R
H
I
R
L
E
N
N
D
N
K
P
Chicken
Gallus gallus
NP_001006391
583
63542
N512
F
V
K
D
V
P
N
N
Q
L
R
H
I
R
L
Frog
Xenopus laevis
NP_001083479
565
61463
R496
D
V
P
N
N
Q
L
R
H
I
R
L
E
N
N
Zebra Danio
Brachydanio rerio
NP_956544
596
63785
S521
F
V
K
D
V
P
N
S
Q
L
R
H
I
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06390
306
36034
K239
E
D
E
Q
K
Y
G
K
A
F
K
V
R
W
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
66.1
80.6
N.A.
66.8
N.A.
N.A.
67
67.9
66.1
74.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77
77.1
80.9
N.A.
77.3
N.A.
N.A.
77.5
78.7
76.1
81.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
0
N.A.
N.A.
0
93.3
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
13.3
N.A.
N.A.
13.3
100
26.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
40
0
0
0
0
0
0
0
30
10
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
30
10
0
0
10
0
0
% E
% Phe:
40
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
30
10
0
0
10
0
0
40
0
0
0
% H
% Ile:
0
0
0
0
0
30
10
0
0
10
0
0
40
0
0
% I
% Lys:
0
0
40
0
10
0
0
10
0
0
10
0
0
30
10
% K
% Leu:
0
0
30
10
0
0
10
30
10
40
0
10
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
10
0
10
10
0
40
10
0
30
40
10
30
20
10
% N
% Pro:
0
0
10
0
0
40
0
0
0
0
0
0
0
0
30
% P
% Gln:
0
30
10
10
0
10
0
0
40
0
0
0
0
0
0
% Q
% Arg:
0
0
0
30
10
0
30
20
0
0
50
0
10
40
0
% R
% Ser:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
50
0
0
40
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _