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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCFC
All Species:
29.39
Human Site:
S496
Identified Species:
71.85
UniProt:
Q9Y5B6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B6
NP_037461.2
917
104804
S496
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Chimpanzee
Pan troglodytes
XP_001164401
917
104831
S496
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Rhesus Macaque
Macaca mulatta
XP_001094648
917
104997
S496
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Dog
Lupus familis
XP_852159
1062
119678
S641
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P58501
917
104583
S496
D
D
I
K
D
E
S
S
E
F
S
S
H
S
S
Rat
Rattus norvegicus
XP_001057305
918
104658
S497
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514256
803
91918
Q407
X
X
X
X
A
L
Y
Q
E
H
A
K
R
R
I
Chicken
Gallus gallus
XP_416707
959
108152
S538
D
D
I
K
D
E
S
S
E
F
S
S
H
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073652
356
39552
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786187
854
97624
S438
D
T
Q
G
D
V
S
S
E
Y
N
F
F
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
84.5
N.A.
95.3
95.6
N.A.
78
82.5
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
99.8
99.2
85.1
N.A.
97.9
97.7
N.A.
83.6
87.4
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
50.7
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
6.6
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
70
0
0
80
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
70
0
0
90
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
70
0
10
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
70
0
0
% H
% Ile:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
70
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
80
80
0
0
70
70
0
70
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _