KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCFC
All Species:
25.15
Human Site:
Y338
Identified Species:
61.48
UniProt:
Q9Y5B6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B6
NP_037461.2
917
104804
Y338
P
A
E
V
N
M
Y
Y
Q
N
T
Y
Q
T
M
Chimpanzee
Pan troglodytes
XP_001164401
917
104831
Y338
P
A
E
V
N
M
Y
Y
Q
N
T
Y
Q
T
M
Rhesus Macaque
Macaca mulatta
XP_001094648
917
104997
Y338
P
T
E
V
N
M
Y
Y
Q
N
T
Y
Q
T
M
Dog
Lupus familis
XP_852159
1062
119678
Y483
P
T
E
V
N
M
Y
Y
Q
N
T
Y
Q
T
M
Cat
Felis silvestris
Mouse
Mus musculus
P58501
917
104583
Y338
P
S
E
V
N
V
Y
Y
Q
N
T
Y
Q
T
M
Rat
Rattus norvegicus
XP_001057305
918
104658
Y339
P
T
E
V
N
M
Y
Y
Q
N
T
Y
Q
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514256
803
91918
E249
Y
G
A
F
G
S
S
E
A
K
S
P
K
T
D
Chicken
Gallus gallus
XP_416707
959
108152
Y380
A
E
V
N
N
L
Y
Y
Q
N
T
Y
Q
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073652
356
39552
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786187
854
97624
E280
G
K
H
E
D
H
N
E
E
L
E
R
W
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
84.5
N.A.
95.3
95.6
N.A.
78
82.5
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
99.8
99.2
85.1
N.A.
97.9
97.7
N.A.
83.6
87.4
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
50.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
6.6
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
93.3
N.A.
20
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
60
10
0
0
0
20
10
0
10
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
10
70
0
10
0
0
70
0
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
70
0
0
0
70
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
0
0
0
10
10
0
0
0
10
0
0
0
0
% S
% Thr:
0
30
0
0
0
0
0
0
0
0
70
0
0
80
0
% T
% Val:
0
0
10
60
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
70
70
0
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _