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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 20
Human Site: S455 Identified Species: 27.5
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 S455 E D L L G R G S R A A L L T E
Chimpanzee Pan troglodytes XP_001152860 569 64563 V31 G E D E Y A N V D A I V V S V
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 G351 I T K N L G F G M G I E F R E
Dog Lupus familis XP_851566 1047 119940 S455 E D L L G R G S R A A L L T E
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 S455 E D L L G R G S R A A L L T E
Rat Rattus norvegicus NP_001100731 1047 119847 S455 E D L L G R G S R A A L L T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 S433 E D L L G R G S R A A L L T E
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 R457 D L L G R G S R A A A L L T E
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 R456 E L L G K G A R S A A L L A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 K461 T E I L G R S K R N A V L E S
Honey Bee Apis mellifera XP_624006 1112 126368 K461 P E I L G R G K R T A V I E S
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 Q455 K K M L G R G Q R S V V L T D
Sea Urchin Strong. purpuratus XP_788298 627 71966 V91 V K M Q K S S V A Y K N L S Q
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 T473 D V M P T K A T L R S D N Q E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 A486 E N Y I T K T A L R S D D H V
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 L476 P D R N S K I L R T K L R G E
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 A467 D S R V G A V A T K N I T S T
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 6.6 6.6 100 N.A. 100 100 N.A. 100 N.A. 46.6 40 N.A. 40 40 46.6 6.6
P-Site Similarity: 100 33.3 6.6 100 N.A. 100 100 N.A. 100 N.A. 53.3 46.6 N.A. 60 66.6 80 26.6
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 6.6 N.A. 6.6 26.6 6.6
P-Site Similarity: N.A. 40 N.A. 40 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 12 12 12 48 53 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 18 36 6 0 0 0 0 0 6 0 0 12 6 0 12 % D
% Glu: 42 18 0 6 0 0 0 0 0 0 0 6 0 12 53 % E
% Phe: 0 0 0 0 0 0 6 0 0 0 0 0 6 0 0 % F
% Gly: 6 0 0 12 53 18 42 6 0 6 0 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 6 0 12 6 0 0 6 0 0 0 12 6 6 0 0 % I
% Lys: 6 12 6 0 12 18 0 12 0 6 12 0 0 0 0 % K
% Leu: 0 12 42 48 6 0 0 6 12 0 0 48 59 0 0 % L
% Met: 0 0 18 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 6 0 12 0 0 6 0 0 6 6 6 6 0 0 % N
% Pro: 12 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 6 0 0 0 6 0 0 0 0 0 6 6 % Q
% Arg: 0 0 12 0 6 48 0 12 53 12 0 0 6 6 0 % R
% Ser: 0 6 0 0 6 6 18 30 6 6 12 0 0 18 12 % S
% Thr: 6 6 0 0 12 0 6 6 6 12 0 0 6 42 6 % T
% Val: 6 6 0 6 0 0 6 12 0 0 6 24 6 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 6 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _