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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 31.21
Human Site: S49 Identified Species: 42.92
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 S49 E E I V Y A K S T A L Q T W L
Chimpanzee Pan troglodytes XP_001152860 569 64563
Rhesus Macaque Macaca mulatta XP_001096507 887 101637
Dog Lupus familis XP_851566 1047 119940 S49 E E I V Y A K S T A L Q T W L
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 S49 E E I V Y A K S T A L Q T W L
Rat Rattus norvegicus NP_001100731 1047 119847 S49 E E I V Y A K S T A L Q T W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 D49 T I M V F C D D K I L F M A S
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 S49 E E I V Y A K S T A L Q T W L
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 S49 E E I V Y A K S T A L Q T W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 M50 V G V E E D V M Y S K S M A L
Honey Bee Apis mellifera XP_624006 1112 126368 S52 T D E D I V Y S K S T A L Q T
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 T49 G E T D N P Y T K T S A L F T
Sea Urchin Strong. purpuratus XP_788298 627 71966
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 S62 D D L R Y L K S S A L D I W L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 S72 D D L R Y L K S S A L N I W L
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 I50 N P Y Q K T T I L H N W L L S
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 N55 E N P E F H K N N A I H F W L
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 13.3 N.A. 100 100 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 0 0 100 N.A. 100 100 N.A. 26.6 N.A. 100 100 N.A. 20 20 20 0
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 46.6 N.A. 46.6 0 33.3
P-Site Similarity: N.A. 73.3 N.A. 73.3 0 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 36 0 0 0 53 0 12 0 12 0 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 18 0 12 0 6 6 6 0 0 0 6 0 0 0 % D
% Glu: 42 42 6 12 6 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 6 6 6 0 % F
% Gly: 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 6 0 6 0 0 0 % H
% Ile: 0 6 36 0 6 0 0 6 0 6 6 0 12 0 0 % I
% Lys: 0 0 0 0 6 0 53 0 18 0 6 0 0 0 0 % K
% Leu: 0 0 12 0 0 12 0 0 6 0 53 0 18 6 59 % L
% Met: 0 0 6 0 0 0 0 6 0 0 0 0 12 0 0 % M
% Asn: 6 6 0 0 6 0 0 6 6 0 6 6 0 0 0 % N
% Pro: 0 6 6 0 0 6 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 6 0 0 0 0 0 0 0 36 0 6 0 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 53 12 12 6 6 0 0 12 % S
% Thr: 12 0 6 0 0 6 6 6 36 6 6 0 36 0 12 % T
% Val: 6 0 6 42 0 6 6 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 53 0 % W
% Tyr: 0 0 6 0 48 0 12 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _