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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUPT16H
All Species:
36.06
Human Site:
S650
Identified Species:
49.58
UniProt:
Q9Y5B9
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B9
NP_009123.1
1047
119914
S650
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Chimpanzee
Pan troglodytes
XP_001152860
569
64563
E210
M
E
I
V
D
A
D
E
K
V
R
H
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001096507
887
101637
I529
P
H
I
R
E
M
K
I
Y
I
D
K
K
Y
E
Dog
Lupus familis
XP_851566
1047
119940
S650
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q920B9
1047
119806
S650
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Rat
Rattus norvegicus
NP_001100731
1047
119847
S650
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506385
1063
120394
S628
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9W603
1035
118422
S652
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Zebra Danio
Brachydanio rerio
NP_001091053
1033
118165
S651
E
G
I
V
K
Q
D
S
L
V
I
N
L
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRG6
1083
123565
T656
E
D
L
V
K
Q
D
T
L
I
L
S
Q
N
K
Honey Bee
Apis mellifera
XP_624006
1112
126368
T656
E
D
L
V
K
Q
D
T
L
I
L
S
Q
N
K
Nematode Worm
Caenorhab. elegans
Q9N5R9
1030
116847
K650
E
G
A
V
K
Q
D
K
L
I
L
S
Q
N
K
Sea Urchin
Strong. purpuratus
XP_788298
627
71966
R269
E
A
H
V
N
G
F
R
Y
T
S
M
R
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6B1
1055
118486
A673
S
D
V
W
I
R
P
A
F
G
G
R
G
R
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82491
1074
120567
S690
L
W
I
R
P
P
F
S
G
R
K
K
I
P
G
Baker's Yeast
Sacchar. cerevisiae
P32558
1035
118612
K668
A
D
V
V
Q
Q
D
K
L
I
E
N
K
T
G
Red Bread Mold
Neurospora crassa
Q8X0X6
1032
118039
R665
K
L
V
E
I
R
N
R
R
P
A
V
L
D
N
Conservation
Percent
Protein Identity:
100
54.2
84.7
99.8
N.A.
98.6
99
N.A.
91.1
N.A.
86.8
83.7
N.A.
58.9
58.5
47
41.1
Protein Similarity:
100
54.3
84.7
100
N.A.
100
100
N.A.
93.7
N.A.
93.5
92.1
N.A.
76.4
75.9
66.5
49.7
P-Site Identity:
100
26.6
6.6
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
46.6
46.6
53.3
13.3
P-Site Similarity:
100
33.3
20
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
86.6
80
13.3
Percent
Protein Identity:
N.A.
36.7
N.A.
34.9
35.4
38.3
Protein Similarity:
N.A.
58.9
N.A.
56.5
55.9
59.6
P-Site Identity:
N.A.
0
N.A.
13.3
33.3
6.6
P-Site Similarity:
N.A.
26.6
N.A.
20
53.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
0
6
0
6
0
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
6
0
71
0
0
0
6
0
0
6
6
% D
% Glu:
65
6
0
6
6
0
0
6
0
0
6
0
0
0
6
% E
% Phe:
0
0
0
0
0
0
12
0
6
0
0
0
0
0
0
% F
% Gly:
0
48
0
0
0
6
0
0
6
6
6
0
6
6
12
% G
% His:
0
6
6
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
59
0
12
0
0
6
0
30
42
0
6
0
0
% I
% Lys:
6
0
0
0
59
0
6
12
6
0
6
12
12
6
24
% K
% Leu:
6
6
12
0
0
0
0
0
65
0
18
0
48
0
6
% L
% Met:
6
0
0
0
0
6
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
6
0
6
0
0
0
0
48
0
59
6
% N
% Pro:
6
0
0
0
6
6
6
0
0
6
0
0
0
6
0
% P
% Gln:
0
0
0
0
6
65
0
0
0
0
0
0
18
0
0
% Q
% Arg:
0
0
0
12
0
12
0
12
6
6
6
6
6
6
42
% R
% Ser:
6
0
0
0
0
0
0
48
0
0
6
18
6
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
6
0
0
0
6
0
% T
% Val:
0
0
18
77
0
0
0
0
0
48
0
6
0
0
0
% V
% Trp:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _