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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUPT16H
All Species:
22.73
Human Site:
T398
Identified Species:
31.25
UniProt:
Q9Y5B9
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B9
NP_009123.1
1047
119914
T398
G
K
K
P
E
E
K
T
Y
A
L
F
I
G
D
Chimpanzee
Pan troglodytes
XP_001152860
569
64563
Rhesus Macaque
Macaca mulatta
XP_001096507
887
101637
K314
Q
L
Q
E
E
L
L
K
E
L
R
H
G
V
K
Dog
Lupus familis
XP_851566
1047
119940
T398
G
K
K
P
E
E
K
T
Y
A
L
F
I
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920B9
1047
119806
T398
G
K
K
P
E
E
K
T
Y
A
L
F
I
G
D
Rat
Rattus norvegicus
NP_001100731
1047
119847
T398
G
K
K
P
E
E
K
T
Y
A
L
F
I
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506385
1063
120394
T376
G
K
K
P
E
E
K
T
Y
A
L
F
V
G
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9W603
1035
118422
T399
G
K
K
P
E
E
K
T
Y
A
L
F
V
G
D
Zebra Danio
Brachydanio rerio
NP_001091053
1033
118165
K398
G
K
K
E
E
Q
K
K
Y
A
L
F
I
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRG6
1083
123565
N399
A
T
D
K
E
G
K
N
Y
A
L
F
I
G
D
Honey Bee
Apis mellifera
XP_624006
1112
126368
I401
A
T
D
K
E
G
K
I
Y
A
L
F
I
G
D
Nematode Worm
Caenorhab. elegans
Q9N5R9
1030
116847
A398
K
G
E
K
G
K
P
A
A
I
A
I
S
D
T
Sea Urchin
Strong. purpuratus
XP_788298
627
71966
K54
T
E
T
S
T
E
D
K
R
K
Q
R
Q
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6B1
1055
118486
F414
T
S
E
K
T
K
Q
F
S
L
L
L
A
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82491
1074
120567
K427
E
S
R
S
K
N
K
K
F
S
L
L
L
A
D
Baker's Yeast
Sacchar. cerevisiae
P32558
1035
118612
L414
Q
S
A
N
N
Y
A
L
Q
L
A
D
T
V
Q
Red Bread Mold
Neurospora crassa
Q8X0X6
1032
118039
V410
P
Q
D
K
N
S
K
V
Y
S
L
I
L
S
D
Conservation
Percent
Protein Identity:
100
54.2
84.7
99.8
N.A.
98.6
99
N.A.
91.1
N.A.
86.8
83.7
N.A.
58.9
58.5
47
41.1
Protein Similarity:
100
54.3
84.7
100
N.A.
100
100
N.A.
93.7
N.A.
93.5
92.1
N.A.
76.4
75.9
66.5
49.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
80
N.A.
60
60
0
6.6
P-Site Similarity:
100
0
13.3
100
N.A.
100
100
N.A.
100
N.A.
100
86.6
N.A.
60
60
13.3
20
Percent
Protein Identity:
N.A.
36.7
N.A.
34.9
35.4
38.3
Protein Similarity:
N.A.
58.9
N.A.
56.5
55.9
59.6
P-Site Identity:
N.A.
6.6
N.A.
20
0
26.6
P-Site Similarity:
N.A.
26.6
N.A.
53.3
0
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
6
0
0
0
6
6
6
53
12
0
6
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
18
0
0
0
6
0
0
0
0
6
0
12
65
% D
% Glu:
6
6
12
12
59
42
0
0
6
0
0
0
0
0
6
% E
% Phe:
0
0
0
0
0
0
0
6
6
0
0
53
0
0
0
% F
% Gly:
42
6
0
0
6
12
0
0
0
0
0
0
6
53
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
6
0
6
0
12
42
0
0
% I
% Lys:
6
42
42
30
6
12
65
24
0
6
0
0
0
0
6
% K
% Leu:
0
6
0
0
0
6
6
6
0
18
71
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
12
6
0
6
0
0
0
0
0
0
0
% N
% Pro:
6
0
0
36
0
0
6
0
0
0
0
0
0
0
0
% P
% Gln:
12
6
6
0
0
6
6
0
6
0
6
0
6
0
6
% Q
% Arg:
0
0
6
0
0
0
0
0
6
0
6
6
0
6
0
% R
% Ser:
0
18
0
12
0
6
0
0
6
12
0
0
6
6
0
% S
% Thr:
12
12
6
0
12
0
0
36
0
0
0
0
6
0
12
% T
% Val:
0
0
0
0
0
0
0
6
0
0
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
0
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _