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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 23.94
Human Site: Y18 Identified Species: 32.92
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 Y18 Y R R V K R L Y S N W R K G E
Chimpanzee Pan troglodytes XP_001152860 569 64563
Rhesus Macaque Macaca mulatta XP_001096507 887 101637
Dog Lupus familis XP_851566 1047 119940 Y18 Y R R V K R L Y S N W R K G E
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 Y18 Y R R V K R L Y S N W R K G E
Rat Rattus norvegicus NP_001100731 1047 119847 Y18 Y R R V K R L Y S N W R K G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 V18 A I V V S V G V D E E I V Y A
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 F18 Y R R I K R F F G S W K K G D
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 Y18 Y R R I K R L Y G N W K K G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 Y19 V R R V K R L Y T E W R A P S
Honey Bee Apis mellifera XP_624006 1112 126368 A21 R M K R L Y T A W K D G E V G
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 E18 D L F F Q R A E R L Y E H W E
Sea Urchin Strong. purpuratus XP_788298 627 71966
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 H31 R L K V F Y D H W K E H K S D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 H41 R A R A L Y E H W K K H S A D
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 Y19 K K R I E L L Y S K Y N E F E
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 A24 H F Y N A W K A D K R S G D A
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 6.6 N.A. 53.3 80 N.A. 60 0 13.3 0
P-Site Similarity: 100 0 0 100 N.A. 100 100 N.A. 6.6 N.A. 86.6 93.3 N.A. 66.6 13.3 26.6 0
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 13.3 N.A. 6.6 33.3 0
P-Site Similarity: N.A. 33.3 N.A. 20 66.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 6 6 0 6 12 0 0 0 0 6 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 0 0 6 0 12 0 6 0 0 6 18 % D
% Glu: 0 0 0 0 6 0 6 6 0 12 12 6 12 0 42 % E
% Phe: 0 6 6 6 6 0 6 6 0 0 0 0 0 6 0 % F
% Gly: 0 0 0 0 0 0 6 0 12 0 0 6 6 36 6 % G
% His: 6 0 0 0 0 0 0 12 0 0 0 12 6 0 0 % H
% Ile: 0 6 0 18 0 0 0 0 0 0 0 6 0 0 0 % I
% Lys: 6 6 12 0 42 0 6 0 0 30 6 12 42 0 0 % K
% Leu: 0 12 0 0 12 6 42 0 0 6 0 0 0 0 0 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 0 0 0 0 30 0 6 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % P
% Gln: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 18 42 53 6 0 48 0 0 6 0 6 30 0 0 0 % R
% Ser: 0 0 0 0 6 0 0 0 30 6 0 6 6 6 6 % S
% Thr: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % T
% Val: 6 0 6 42 0 6 0 6 0 0 0 0 6 6 0 % V
% Trp: 0 0 0 0 0 6 0 0 18 0 42 0 0 6 0 % W
% Tyr: 36 0 6 0 0 18 0 42 0 0 12 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _