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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUPT16H
All Species:
40.61
Human Site:
Y243
Identified Species:
55.83
UniProt:
Q9Y5B9
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B9
NP_009123.1
1047
119914
Y243
P
S
T
V
E
M
C
Y
P
P
I
I
Q
S
G
Chimpanzee
Pan troglodytes
XP_001152860
569
64563
Rhesus Macaque
Macaca mulatta
XP_001096507
887
101637
I172
S
A
V
V
A
Y
T
I
A
V
K
E
D
G
E
Dog
Lupus familis
XP_851566
1047
119940
Y243
P
S
T
V
E
M
C
Y
P
P
I
I
Q
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q920B9
1047
119806
Y243
P
S
T
V
E
M
C
Y
P
P
I
I
Q
S
G
Rat
Rattus norvegicus
NP_001100731
1047
119847
Y243
P
S
T
V
E
M
C
Y
P
P
I
I
Q
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506385
1063
120394
Y231
I
I
Q
S
G
G
N
Y
N
L
K
F
S
V
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9W603
1035
118422
Y244
P
S
T
I
E
M
C
Y
P
P
I
I
Q
S
G
Zebra Danio
Brachydanio rerio
NP_001091053
1033
118165
Y243
P
S
T
V
E
M
C
Y
P
P
I
I
Q
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRG6
1083
123565
Y244
P
R
L
L
D
M
A
Y
P
P
I
I
Q
S
G
Honey Bee
Apis mellifera
XP_624006
1112
126368
Y246
V
T
Q
V
D
M
C
Y
P
A
I
I
Q
S
G
Nematode Worm
Caenorhab. elegans
Q9N5R9
1030
116847
Y240
K
Y
E
A
D
T
C
Y
D
P
I
V
M
S
G
Sea Urchin
Strong. purpuratus
XP_788298
627
71966
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6B1
1055
118486
Y256
P
D
N
V
D
I
C
Y
P
P
V
F
Q
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82491
1074
120567
Y269
P
E
N
V
D
I
C
Y
P
P
I
F
Q
S
G
Baker's Yeast
Sacchar. cerevisiae
P32558
1035
118612
S258
D
L
L
D
W
T
Y
S
P
I
I
Q
S
G
K
Red Bread Mold
Neurospora crassa
Q8X0X6
1032
118039
L255
P
E
Q
L
D
W
I
L
G
P
I
V
Q
S
G
Conservation
Percent
Protein Identity:
100
54.2
84.7
99.8
N.A.
98.6
99
N.A.
91.1
N.A.
86.8
83.7
N.A.
58.9
58.5
47
41.1
Protein Similarity:
100
54.3
84.7
100
N.A.
100
100
N.A.
93.7
N.A.
93.5
92.1
N.A.
76.4
75.9
66.5
49.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
100
N.A.
66.6
66.6
40
0
P-Site Similarity:
100
0
13.3
100
N.A.
100
100
N.A.
6.6
N.A.
100
100
N.A.
80
80
53.3
0
Percent
Protein Identity:
N.A.
36.7
N.A.
34.9
35.4
38.3
Protein Similarity:
N.A.
58.9
N.A.
56.5
55.9
59.6
P-Site Identity:
N.A.
60
N.A.
66.6
13.3
40
P-Site Similarity:
N.A.
80
N.A.
80
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
6
0
6
0
6
6
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
0
6
36
0
0
0
6
0
0
0
6
0
0
% D
% Glu:
0
12
6
0
36
0
0
0
0
0
0
6
0
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
18
0
0
0
% F
% Gly:
0
0
0
0
6
6
0
0
6
0
0
0
0
12
71
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
6
0
12
6
6
0
6
71
48
0
0
0
% I
% Lys:
6
0
0
0
0
0
0
0
0
0
12
0
0
0
6
% K
% Leu:
0
6
12
12
0
0
0
6
0
6
0
0
0
0
0
% L
% Met:
0
0
0
0
0
48
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
12
0
0
0
6
0
6
0
0
0
0
0
0
% N
% Pro:
59
0
0
0
0
0
0
0
65
65
0
0
0
0
0
% P
% Gln:
0
0
18
0
0
0
0
0
0
0
0
6
65
0
0
% Q
% Arg:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
36
0
6
0
0
0
6
0
0
0
0
12
71
0
% S
% Thr:
0
6
36
0
0
12
6
0
0
0
0
0
0
0
0
% T
% Val:
6
0
6
53
0
0
0
0
0
6
6
12
0
6
6
% V
% Trp:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
6
6
71
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _