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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 40.91
Human Site: Y282 Identified Species: 56.25
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 Y282 M G I R F K S Y C S N L V R T
Chimpanzee Pan troglodytes XP_001152860 569 64563
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 K211 E I V D A D E K V R H S K L A
Dog Lupus familis XP_851566 1047 119940 Y282 M G I R F K S Y C S N L V R T
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 Y282 M G I R F K S Y C S N L V R T
Rat Rattus norvegicus NP_001100731 1047 119847 Y282 M G I R F K S Y C S N L V R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 V270 N L V R T L M V D P P Q E V Q
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 Y283 L G I R Y K S Y C S N L V R T
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 Y282 M G I R Y K S Y C S N L V R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 Y283 L G A R Y K S Y C S N I S R T
Honey Bee Apis mellifera XP_624006 1112 126368 Y285 L G A R Y K S Y C S N I V R T
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 S279 T S F G A R L S E Y C T N L T
Sea Urchin Strong. purpuratus XP_788298 627 71966
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 Y295 I C A I G S K Y S S Y C S N V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 Y308 I C A V G A R Y N S Y C S N V
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 Y297 C G I R Y N N Y C S N I T R T
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 Y294 M G L R Y K S Y C S Q I A R T
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 6.6 N.A. 86.6 93.3 N.A. 66.6 73.3 6.6 0
P-Site Similarity: 100 0 13.3 100 N.A. 100 100 N.A. 13.3 N.A. 100 100 N.A. 86.6 93.3 13.3 0
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 13.3 N.A. 13.3 60 66.6
P-Site Similarity: N.A. 20 N.A. 20 80 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 0 12 6 0 0 0 0 0 0 6 0 6 % A
% Cys: 6 12 0 0 0 0 0 0 59 0 6 12 0 0 0 % C
% Asp: 0 0 0 6 0 6 0 0 6 0 0 0 0 0 0 % D
% Glu: 6 0 0 0 0 0 6 0 6 0 0 0 6 0 0 % E
% Phe: 0 0 6 0 24 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 59 0 6 12 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % H
% Ile: 12 6 42 6 0 0 0 0 0 0 0 24 0 0 0 % I
% Lys: 0 0 0 0 0 53 6 6 0 0 0 0 6 0 0 % K
% Leu: 18 6 6 0 0 6 6 0 0 0 0 36 0 12 0 % L
% Met: 36 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 0 6 6 0 6 0 53 0 6 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 6 6 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 6 6 0 0 6 % Q
% Arg: 0 0 0 65 0 6 6 0 0 6 0 0 0 59 0 % R
% Ser: 0 6 0 0 0 6 53 6 6 71 0 6 18 0 0 % S
% Thr: 6 0 0 0 6 0 0 0 0 0 0 6 6 0 65 % T
% Val: 0 0 12 6 0 0 0 6 6 0 0 0 42 6 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 36 0 0 71 0 6 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _