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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 34.85
Human Site: Y893 Identified Species: 47.92
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 Y893 L N S C D L K Y T E G V Q S L
Chimpanzee Pan troglodytes XP_001152860 569 64563 T419 D G P A T V L T S V K K K V K
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 D737 F G K K R H T D V Q F Y T E V
Dog Lupus familis XP_851566 1047 119940 Y893 L N S C D L K Y T E G V Q S L
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 Y893 L N S C D L K Y T E G V Q S L
Rat Rattus norvegicus NP_001100731 1047 119847 Y893 L N S C D L K Y T E G V Q S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 Y871 L N S C D L K Y T E G V Q S L
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 K885 M A S L D P I K E W L N S C D
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 S879 I N A V P V N S L D P I K E W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 Y899 L N S C D I R Y S E G V Q S L
Honey Bee Apis mellifera XP_624006 1112 126368 Y899 L N S C D I R Y T E G V Q S L
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 S878 V A Q I P M S S I D K I K E W
Sea Urchin Strong. purpuratus XP_788298 627 71966 G477 C D I K Y T E G V Q S L N W P
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 L899 L D A I K E W L D T T D L K Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 Y920 L D T T D I K Y Y E S K L N L
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 N882 R V Q F G L K N F D M V F V Y
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 F875 L K N F D L V F V F K D F T R
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 100 N.A. 13.3 6.6 N.A. 80 86.6 0 0
P-Site Similarity: 100 20 13.3 100 N.A. 100 100 N.A. 100 N.A. 20 46.6 N.A. 100 100 33.3 26.6
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 6.6 N.A. 40 20 20
P-Site Similarity: N.A. 20 N.A. 66.6 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 6 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 6 0 0 42 0 0 0 0 0 0 0 0 0 6 0 % C
% Asp: 6 18 0 0 59 0 0 6 6 18 0 12 0 0 6 % D
% Glu: 0 0 0 0 0 6 6 0 6 48 0 0 0 18 0 % E
% Phe: 6 0 0 12 0 0 0 6 6 6 6 0 12 0 0 % F
% Gly: 0 12 0 0 6 0 0 6 0 0 42 0 0 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 6 12 0 18 6 0 6 0 0 12 0 0 0 % I
% Lys: 0 6 6 12 6 0 42 6 0 0 18 12 18 6 6 % K
% Leu: 59 0 0 6 0 42 6 6 6 0 6 6 12 0 48 % L
% Met: 6 0 0 0 0 6 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 48 6 0 0 0 6 6 0 0 0 6 6 6 0 % N
% Pro: 0 0 6 0 12 6 0 0 0 0 6 0 0 0 6 % P
% Gln: 0 0 12 0 0 0 0 0 0 12 0 0 42 0 0 % Q
% Arg: 6 0 0 0 6 0 12 0 0 0 0 0 0 0 6 % R
% Ser: 0 0 48 0 0 0 6 12 12 0 12 0 6 42 0 % S
% Thr: 0 0 6 6 6 6 6 6 36 6 6 0 6 6 0 % T
% Val: 6 6 0 6 0 12 6 0 18 6 0 48 0 12 6 % V
% Trp: 0 0 0 0 0 0 6 0 0 6 0 0 0 6 12 % W
% Tyr: 0 0 0 0 6 0 0 48 6 0 0 6 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _