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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPTL3
All Species:
13.03
Human Site:
S218
Identified Species:
31.85
UniProt:
Q9Y5C1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5C1
NP_055310.1
460
53637
S218
P
T
E
I
S
L
S
S
K
P
R
A
P
R
T
Chimpanzee
Pan troglodytes
XP_001159650
460
53624
S218
P
T
E
I
S
L
S
S
K
P
R
A
P
R
T
Rhesus Macaque
Macaca mulatta
XP_001086114
457
53306
S218
P
T
E
I
S
L
S
S
K
P
R
A
P
R
T
Dog
Lupus familis
XP_536686
459
53805
K218
T
E
N
S
L
S
S
K
P
R
A
P
R
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R182
455
52524
S218
P
S
E
N
S
L
S
S
K
S
R
A
P
R
T
Rat
Rattus norvegicus
Q6TMA8
405
44932
N176
Q
L
I
G
L
T
P
N
A
T
R
L
H
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518416
293
33863
R64
S
Q
R
S
F
V
E
R
Q
D
S
K
I
K
N
Chicken
Gallus gallus
NP_001128594
464
53460
E219
L
A
E
N
S
F
L
E
E
Q
A
E
S
N
E
Frog
Xenopus laevis
Q5XK91
457
51018
D217
G
R
P
R
L
K
A
D
L
Q
R
A
P
S
R
Zebra Danio
Brachydanio rerio
NP_571893
458
52448
L222
T
I
E
K
P
M
D
L
N
P
E
T
P
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.6
87.8
N.A.
75.6
31
N.A.
37.6
55.5
23
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.3
94.1
N.A.
87.3
50.8
N.A.
51.7
73.4
42.1
66
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
80
13.3
N.A.
0
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
86.6
20
N.A.
20
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
10
0
20
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
10
0
0
0
10
0
% D
% Glu:
0
10
60
0
0
0
10
10
10
0
10
10
0
0
10
% E
% Phe:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
30
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
10
0
10
40
0
0
10
0
10
0
% K
% Leu:
10
10
0
0
30
40
10
10
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
20
0
0
0
10
10
0
0
0
0
10
10
% N
% Pro:
40
0
10
0
10
0
10
0
10
40
0
10
60
0
20
% P
% Gln:
10
10
0
0
0
0
0
0
10
20
0
0
0
0
0
% Q
% Arg:
0
10
10
10
0
0
0
10
0
10
60
0
10
50
10
% R
% Ser:
10
10
0
20
50
10
50
40
0
10
10
0
10
10
0
% S
% Thr:
20
30
0
0
0
10
0
0
0
10
0
10
0
10
50
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _