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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN16
All Species:
12.12
Human Site:
T293
Identified Species:
29.63
UniProt:
Q9Y5I7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5I7
NP_006571.1
305
33836
T293
K
S
Y
S
A
P
R
T
E
T
A
K
M
Y
A
Chimpanzee
Pan troglodytes
XP_001161102
305
33850
T293
K
S
Y
S
A
P
R
T
E
T
A
K
M
Y
A
Rhesus Macaque
Macaca mulatta
XP_001093252
235
26008
E224
S
Y
S
A
A
R
T
E
T
A
K
M
Y
A
V
Dog
Lupus familis
XP_850268
286
31702
T274
K
S
Y
A
A
P
R
T
E
T
A
K
M
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q925N4
235
26081
E224
S
Y
K
A
P
R
T
E
T
A
K
M
Y
A
V
Rat
Rattus norvegicus
Q91Y55
235
26072
E224
S
Y
K
A
P
R
T
E
T
A
K
M
Y
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512461
252
27453
T241
V
A
A
S
V
A
V
T
V
A
A
A
V
P
V
Chicken
Gallus gallus
XP_426702
247
27291
A236
H
L
P
S
S
Q
T
A
T
A
K
M
Y
A
V
Frog
Xenopus laevis
NP_001087995
210
22636
Q199
R
G
Q
Q
Y
Y
R
Q
S
Q
P
S
A
T
T
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
S204
K
S
S
R
P
V
K
S
S
R
P
P
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
73.4
76.3
N.A.
71.4
71.1
N.A.
51.7
62.6
25.5
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
74.4
80.9
N.A.
73.7
73.4
N.A.
62.2
69.8
37.7
32.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
0
0
N.A.
20
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
6.6
6.6
N.A.
33.3
13.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
40
40
10
0
10
0
50
40
10
10
40
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
30
30
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
20
0
0
0
10
0
0
0
40
30
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
40
30
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
30
30
0
0
0
0
20
10
0
10
0
% P
% Gln:
0
0
10
10
0
10
0
10
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
30
40
0
0
10
0
0
0
0
0
% R
% Ser:
30
40
20
40
10
0
0
10
20
0
0
10
10
10
10
% S
% Thr:
0
0
0
0
0
0
40
40
40
30
0
0
0
10
10
% T
% Val:
10
0
0
0
10
10
10
0
10
0
0
0
10
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
30
0
10
10
0
0
0
0
0
0
40
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _