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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEY1 All Species: 13.64
Human Site: S38 Identified Species: 30
UniProt: Q9Y5J3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5J3 NP_001035798.1 304 32613 S38 N L S S A L G S M S P T T S S
Chimpanzee Pan troglodytes XP_001167373 266 28499 I18 A R K R R R G I I E K R R R D
Rhesus Macaque Macaca mulatta XP_001090360 304 32580 S38 N L S S A L G S M S P T T S S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WV93 299 32045 S38 N L S S A L C S M S P T T S S
Rat Rattus norvegicus Q04666 281 29603 E33 D K P K T A S E H R K S S K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521532 320 33658 T43 V P D G L V G T P D P A S S S
Chicken Gallus gallus O57337 290 31053 S38 S A S E H R K S S K P I M E K
Frog Xenopus laevis Q9I8A3 294 32117 T38 L S S M S P S T S S Q I L A R
Zebra Danio Brachydanio rerio Q8AXV6 317 33920 M38 A N S P L G S M S P S T T S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KM13 425 46797 L98 S E P G S C Q L M S R K K R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783676 317 34739 R38 R G I I E K R R R D R I N N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 99.3 N.A. N.A. 94.4 30.5 N.A. 59.3 25.9 81.2 69 N.A. 32.9 N.A. N.A. 48.2
Protein Similarity: 100 87.5 99.3 N.A. N.A. 95.3 43.7 N.A. 69 42.4 87.5 78.5 N.A. 45.8 N.A. N.A. 59.9
P-Site Identity: 100 6.6 100 N.A. N.A. 93.3 0 N.A. 26.6 20 13.3 26.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 N.A. N.A. 93.3 20 N.A. 46.6 26.6 33.3 26.6 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 28 10 0 0 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 0 19 0 0 0 0 10 % D
% Glu: 0 10 0 10 10 0 0 10 0 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 19 0 10 37 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 10 0 0 0 10 10 0 0 28 0 0 0 % I
% Lys: 0 10 10 10 0 10 10 0 0 10 19 10 10 10 10 % K
% Leu: 10 28 0 0 19 28 0 10 0 0 0 0 10 0 0 % L
% Met: 0 0 0 10 0 0 0 10 37 0 0 0 10 0 0 % M
% Asn: 28 10 0 0 0 0 0 0 0 0 0 0 10 10 0 % N
% Pro: 0 10 19 10 0 10 0 0 10 10 46 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % Q
% Arg: 10 10 0 10 10 19 10 10 10 10 19 10 10 19 19 % R
% Ser: 19 10 55 28 19 0 28 37 28 46 10 10 19 46 46 % S
% Thr: 0 0 0 0 10 0 0 19 0 0 0 37 37 0 0 % T
% Val: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _