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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEY1
All Species:
12.42
Human Site:
S44
Identified Species:
27.33
UniProt:
Q9Y5J3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5J3
NP_001035798.1
304
32613
S44
G
S
M
S
P
T
T
S
S
Q
I
L
A
R
K
Chimpanzee
Pan troglodytes
XP_001167373
266
28499
R24
G
I
I
E
K
R
R
R
D
R
I
N
N
S
L
Rhesus Macaque
Macaca mulatta
XP_001090360
304
32580
S44
G
S
M
S
P
T
T
S
S
Q
I
L
A
R
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV93
299
32045
S44
C
S
M
S
P
T
T
S
S
Q
V
L
A
R
K
Rat
Rattus norvegicus
Q04666
281
29603
K39
S
E
H
R
K
S
S
K
P
I
M
E
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521532
320
33658
S49
G
T
P
D
P
A
S
S
S
K
E
K
R
P
P
Chicken
Gallus gallus
O57337
290
31053
E44
K
S
S
K
P
I
M
E
K
R
R
R
A
R
I
Frog
Xenopus laevis
Q9I8A3
294
32117
A44
S
T
S
S
Q
I
L
A
R
K
R
R
R
G
I
Zebra Danio
Brachydanio rerio
Q8AXV6
317
33920
S44
S
M
S
P
S
T
T
S
Q
V
Q
A
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
R104
Q
L
M
S
R
K
K
R
R
G
V
I
E
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
N44
R
R
R
D
R
I
N
N
S
L
T
E
L
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
99.3
N.A.
N.A.
94.4
30.5
N.A.
59.3
25.9
81.2
69
N.A.
32.9
N.A.
N.A.
48.2
Protein Similarity:
100
87.5
99.3
N.A.
N.A.
95.3
43.7
N.A.
69
42.4
87.5
78.5
N.A.
45.8
N.A.
N.A.
59.9
P-Site Identity:
100
13.3
100
N.A.
N.A.
86.6
6.6
N.A.
26.6
26.6
6.6
20
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
N.A.
N.A.
93.3
33.3
N.A.
46.6
33.3
26.6
33.3
N.A.
40
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
10
37
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
0
10
0
0
10
19
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
28
0
0
0
10
28
10
0
0
19
% I
% Lys:
10
0
0
10
19
10
10
10
10
19
0
10
10
19
37
% K
% Leu:
0
10
0
0
0
0
10
0
0
10
0
28
10
0
10
% L
% Met:
0
10
37
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
10
10
0
0
% N
% Pro:
0
0
10
10
46
0
0
0
10
0
0
0
0
10
10
% P
% Gln:
10
0
0
0
10
0
0
0
10
28
10
0
0
0
0
% Q
% Arg:
10
10
10
10
19
10
10
19
19
19
19
19
28
55
28
% R
% Ser:
28
37
28
46
10
10
19
46
46
0
0
0
0
10
0
% S
% Thr:
0
19
0
0
0
37
37
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _