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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEY1 All Species: 12.42
Human Site: S45 Identified Species: 27.33
UniProt: Q9Y5J3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5J3 NP_001035798.1 304 32613 S45 S M S P T T S S Q I L A R K R
Chimpanzee Pan troglodytes XP_001167373 266 28499 D25 I I E K R R R D R I N N S L S
Rhesus Macaque Macaca mulatta XP_001090360 304 32580 S45 S M S P T T S S Q I L A R K R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WV93 299 32045 S45 S M S P T T S S Q V L A R K R
Rat Rattus norvegicus Q04666 281 29603 P40 E H R K S S K P I M E K R R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521532 320 33658 S50 T P D P A S S S K E K R P P Q
Chicken Gallus gallus O57337 290 31053 K45 S S K P I M E K R R R A R I N
Frog Xenopus laevis Q9I8A3 294 32117 R45 T S S Q I L A R K R R R G I I
Zebra Danio Brachydanio rerio Q8AXV6 317 33920 Q45 M S P S T T S Q V Q A R K R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KM13 425 46797 R105 L M S R K K R R G V I E K K R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783676 317 34739 S45 R R D R I N N S L T E L R R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 99.3 N.A. N.A. 94.4 30.5 N.A. 59.3 25.9 81.2 69 N.A. 32.9 N.A. N.A. 48.2
Protein Similarity: 100 87.5 99.3 N.A. N.A. 95.3 43.7 N.A. 69 42.4 87.5 78.5 N.A. 45.8 N.A. N.A. 59.9
P-Site Identity: 100 6.6 100 N.A. N.A. 93.3 13.3 N.A. 20 26.6 6.6 26.6 N.A. 26.6 N.A. N.A. 13.3
P-Site Similarity: 100 20 100 N.A. N.A. 100 40 N.A. 46.6 33.3 26.6 40 N.A. 46.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 0 10 37 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 10 0 0 10 19 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 28 0 0 0 10 28 10 0 0 19 10 % I
% Lys: 0 0 10 19 10 10 10 10 19 0 10 10 19 37 0 % K
% Leu: 10 0 0 0 0 10 0 0 10 0 28 10 0 10 10 % L
% Met: 10 37 0 0 0 10 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 10 10 0 0 10 % N
% Pro: 0 10 10 46 0 0 0 10 0 0 0 0 10 10 0 % P
% Gln: 0 0 0 10 0 0 0 10 28 10 0 0 0 0 10 % Q
% Arg: 10 10 10 19 10 10 19 19 19 19 19 28 55 28 55 % R
% Ser: 37 28 46 10 10 19 46 46 0 0 0 0 10 0 10 % S
% Thr: 19 0 0 0 37 37 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _