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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEY1
All Species:
20
Human Site:
S70
Identified Species:
44
UniProt:
Q9Y5J3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5J3
NP_001035798.1
304
32613
S70
D
R
I
N
N
S
L
S
E
L
R
R
L
V
P
Chimpanzee
Pan troglodytes
XP_001167373
266
28499
F42
R
R
L
V
P
S
A
F
E
K
Q
G
S
A
K
Rhesus Macaque
Macaca mulatta
XP_001090360
304
32580
S70
D
R
I
N
N
S
L
S
E
L
R
R
L
V
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV93
299
32045
S70
D
R
I
N
N
S
L
S
E
L
R
R
L
V
P
Rat
Rattus norvegicus
Q04666
281
29603
L57
I
N
E
S
L
S
Q
L
K
T
L
I
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521532
320
33658
S86
P
E
T
S
S
P
V
S
A
R
K
R
R
R
G
Chicken
Gallus gallus
O57337
290
31053
L66
K
M
L
I
L
D
A
L
K
K
D
S
S
R
H
Frog
Xenopus laevis
Q9I8A3
294
32117
S65
D
R
I
N
N
S
L
S
E
L
R
R
L
V
P
Zebra Danio
Brachydanio rerio
Q8AXV6
317
33920
S69
D
R
I
N
N
S
L
S
E
L
R
R
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
E122
R
I
N
S
S
L
T
E
L
K
R
L
V
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
A68
G
S
A
K
L
E
K
A
E
I
L
Q
M
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
99.3
N.A.
N.A.
94.4
30.5
N.A.
59.3
25.9
81.2
69
N.A.
32.9
N.A.
N.A.
48.2
Protein Similarity:
100
87.5
99.3
N.A.
N.A.
95.3
43.7
N.A.
69
42.4
87.5
78.5
N.A.
45.8
N.A.
N.A.
59.9
P-Site Identity:
100
20
100
N.A.
N.A.
100
13.3
N.A.
13.3
0
100
100
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
N.A.
N.A.
100
26.6
N.A.
40
13.3
100
100
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
19
10
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% D
% Glu:
0
10
10
0
0
10
0
10
64
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
10
46
10
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
10
0
0
10
0
0
10
0
19
28
10
0
0
0
10
% K
% Leu:
0
0
19
0
28
10
46
19
10
46
19
10
55
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
46
46
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
10
0
0
0
0
0
0
0
10
46
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% Q
% Arg:
19
55
0
0
0
0
0
0
0
10
55
55
10
19
0
% R
% Ser:
0
10
0
28
19
64
0
55
0
0
0
10
19
0
10
% S
% Thr:
0
0
10
0
0
0
10
0
0
10
0
0
0
10
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
10
46
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _