KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEY1
All Species:
14.55
Human Site:
T106
Identified Species:
32
UniProt:
Q9Y5J3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5J3
NP_001035798.1
304
32613
T106
D
H
L
K
M
L
H
T
A
G
G
K
G
Y
F
Chimpanzee
Pan troglodytes
XP_001167373
266
28499
H78
G
K
G
Y
F
D
A
H
A
L
A
M
D
Y
R
Rhesus Macaque
Macaca mulatta
XP_001090360
304
32580
T106
D
H
L
K
M
L
H
T
A
G
G
K
G
Y
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV93
299
32045
T106
D
H
L
K
M
L
H
T
A
G
G
K
G
Y
F
Rat
Rattus norvegicus
Q04666
281
29603
R93
K
H
L
R
N
L
Q
R
A
Q
M
T
A
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521532
320
33658
V122
P
S
A
F
E
K
Q
V
R
I
L
Q
M
T
V
Chicken
Gallus gallus
O57337
290
31053
S102
A
Q
M
A
A
A
L
S
A
D
P
S
V
L
G
Frog
Xenopus laevis
Q9I8A3
294
32117
T101
D
H
L
K
M
L
H
T
A
G
G
K
G
Y
F
Zebra Danio
Brachydanio rerio
Q8AXV6
317
33920
A105
D
H
L
K
M
L
H
A
A
G
G
K
G
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
K158
H
L
K
S
L
Q
S
K
T
L
D
S
L
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
R104
H
A
Y
A
M
D
Y
R
V
L
G
F
R
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
99.3
N.A.
N.A.
94.4
30.5
N.A.
59.3
25.9
81.2
69
N.A.
32.9
N.A.
N.A.
48.2
Protein Similarity:
100
87.5
99.3
N.A.
N.A.
95.3
43.7
N.A.
69
42.4
87.5
78.5
N.A.
45.8
N.A.
N.A.
59.9
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
26.6
N.A.
0
6.6
100
93.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
N.A.
N.A.
100
33.3
N.A.
6.6
20
100
93.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
19
10
10
10
10
73
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
46
0
0
0
0
19
0
0
0
10
10
0
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
46
% F
% Gly:
10
0
10
0
0
0
0
0
0
46
55
0
46
0
10
% G
% His:
19
55
0
0
0
0
46
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
10
10
46
0
10
0
10
0
0
0
46
0
0
0
% K
% Leu:
0
10
55
0
10
55
10
0
0
28
10
0
10
10
10
% L
% Met:
0
0
10
0
55
0
0
0
0
0
10
10
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
19
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
19
10
0
0
0
10
0
10
% R
% Ser:
0
10
0
10
0
0
10
10
0
0
0
19
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
37
10
0
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
10
0
0
0
0
0
0
55
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _