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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPO11 All Species: 16.06
Human Site: S43 Identified Species: 32.12
UniProt: Q9Y5K1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5K1 NP_036576.1 396 44537 S43 T G G S R L A S S S E V L A S
Chimpanzee Pan troglodytes XP_514741 396 44516 S43 S G G S R L A S S S E V L A S
Rhesus Macaque Macaca mulatta XP_001088572 396 44490 S43 S G G S R V A S S S E V L V S
Dog Lupus familis XP_853487 396 44228 S43 G G G T P Q A S S S E V L A S
Cat Felis silvestris
Mouse Mus musculus Q9WTK8 396 44551 S43 A G A T R V A S S S E V L T A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991245 383 43293 V34 E D I S S Q D V L T R I E K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22236 425 49150 E52 E Q A M R K I E F A L A D I K
Sea Urchin Strong. purpuratus XP_001202309 352 39838
Poplar Tree Populus trichocarpa XP_002326329 423 47099 A70 S S S C R E V A D L S L T S V
Maize Zea mays NP_001141583 436 47745 A83 A S S Y I V V A D Q D S T S V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZ03 427 47427 A74 S S S C R E V A D L S L S S V
Baker's Yeast Sacchar. cerevisiae P23179 398 45394 C40 G H S N G T P C S N A D V L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.4 90.4 N.A. 82.5 N.A. N.A. N.A. N.A. N.A. 58.3 N.A. N.A. N.A. 28.2 43.6
Protein Similarity: 100 100 98.9 96.2 N.A. 93.1 N.A. N.A. N.A. N.A. N.A. 77 N.A. N.A. N.A. 48.4 67.4
P-Site Identity: 100 93.3 80 73.3 N.A. 60 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 93.3 80 N.A. 80 N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. 13.3 0
Percent
Protein Identity: 33.3 34.6 N.A. 33.4 22.3 N.A.
Protein Similarity: 55.7 55.9 N.A. 56.2 44.2 N.A.
P-Site Identity: 6.6 0 N.A. 6.6 6.6 N.A.
P-Site Similarity: 33.3 26.6 N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 17 0 0 0 42 25 0 9 9 9 0 25 17 % A
% Cys: 0 0 0 17 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 0 25 0 9 9 9 0 0 % D
% Glu: 17 0 0 0 0 17 0 9 0 0 42 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 17 42 34 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 9 0 0 0 0 9 0 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % K
% Leu: 0 0 0 0 0 17 0 0 9 17 9 17 42 9 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 17 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 59 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 34 25 34 34 9 0 0 42 50 42 17 9 9 25 34 % S
% Thr: 9 0 0 17 0 9 0 0 0 9 0 0 17 9 0 % T
% Val: 0 0 0 0 0 25 25 9 0 0 0 42 9 9 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _