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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPO11 All Species: 30
Human Site: T257 Identified Species: 60
UniProt: Q9Y5K1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5K1 NP_036576.1 396 44537 T257 K G V P D L N T R L L V K K L
Chimpanzee Pan troglodytes XP_514741 396 44516 T257 K G V P D L N T R L L V K K L
Rhesus Macaque Macaca mulatta XP_001088572 396 44490 T257 K G V P D L N T R L L V K K L
Dog Lupus familis XP_853487 396 44228 T257 K G V P D L N T R L L V K K L
Cat Felis silvestris
Mouse Mus musculus Q9WTK8 396 44551 T257 K G V P D L N T R L L V K K L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991245 383 43293 V248 D V N S R L M V R K L W D A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22236 425 49150 T266 H G I E I Y L T Y K Y G P T K
Sea Urchin Strong. purpuratus XP_001202309 352 39838 V217 D I N T R M M V R K L W D T L
Poplar Tree Populus trichocarpa XP_002326329 423 47099 T284 K G Q P D V A T R L F L R K M
Maize Zea mays NP_001141583 436 47745 T297 K G Q P D V A T R L F L R R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZ03 427 47427 T288 K G Q P D V A T R L F L R K M
Baker's Yeast Sacchar. cerevisiae P23179 398 45394 L254 K L S T N T M L I T G K G F P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.4 90.4 N.A. 82.5 N.A. N.A. N.A. N.A. N.A. 58.3 N.A. N.A. N.A. 28.2 43.6
Protein Similarity: 100 100 98.9 96.2 N.A. 93.1 N.A. N.A. N.A. N.A. N.A. 77 N.A. N.A. N.A. 48.4 67.4
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: 33.3 34.6 N.A. 33.4 22.3 N.A.
Protein Similarity: 55.7 55.9 N.A. 56.2 44.2 N.A.
P-Site Identity: 53.3 53.3 N.A. 53.3 6.6 N.A.
P-Site Similarity: 80 80 N.A. 80 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 25 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 0 67 0 0 0 0 0 0 0 17 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 25 0 0 9 0 % F
% Gly: 0 75 0 0 0 0 0 0 0 0 9 9 9 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 9 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 75 0 0 0 0 0 0 0 0 25 0 9 42 59 9 % K
% Leu: 0 9 0 0 0 50 9 9 0 67 59 25 0 0 67 % L
% Met: 0 0 0 0 0 9 25 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 17 0 9 0 42 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 67 0 0 0 0 0 0 0 0 9 0 9 % P
% Gln: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 0 0 0 84 0 0 0 25 9 0 % R
% Ser: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 17 0 9 0 75 0 9 0 0 0 17 0 % T
% Val: 0 9 42 0 0 25 0 17 0 0 0 42 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 9 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _