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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPO11 All Species: 17.27
Human Site: T97 Identified Species: 34.55
UniProt: Q9Y5K1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5K1 NP_036576.1 396 44537 T97 Q M V S H C T T R K I K S D S
Chimpanzee Pan troglodytes XP_514741 396 44516 T97 Q M V S H C T T R K I K S D S
Rhesus Macaque Macaca mulatta XP_001088572 396 44490 T97 Q M V S H C T T R K I K S D S
Dog Lupus familis XP_853487 396 44228 T97 Q M V T H F T T R K I K S D S
Cat Felis silvestris
Mouse Mus musculus Q9WTK8 396 44551 T97 R M I P Q C T T R K I R S D S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_991245 383 43293 H88 D V S P K Y L H C G K P T T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22236 425 49150 L106 L H Q V Y D L L E N D K R S T
Sea Urchin Strong. purpuratus XP_001202309 352 39838 R57 D A K M T E V R F D V P T S T
Poplar Tree Populus trichocarpa XP_002326329 423 47099 K124 D R I V L K D K N T L R P F A
Maize Zea mays NP_001141583 436 47745 R137 D R I V L V R R E S A R P F A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZ03 427 47427 K128 D R I V L K D K S T L R P F A
Baker's Yeast Sacchar. cerevisiae P23179 398 45394 N94 T T L D F P L N G P H L C T H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.4 90.4 N.A. 82.5 N.A. N.A. N.A. N.A. N.A. 58.3 N.A. N.A. N.A. 28.2 43.6
Protein Similarity: 100 100 98.9 96.2 N.A. 93.1 N.A. N.A. N.A. N.A. N.A. 77 N.A. N.A. N.A. 48.4 67.4
P-Site Identity: 100 100 100 86.6 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. 20 20
Percent
Protein Identity: 33.3 34.6 N.A. 33.4 22.3 N.A.
Protein Similarity: 55.7 55.9 N.A. 56.2 44.2 N.A.
P-Site Identity: 0 0 N.A. 0 0 N.A.
P-Site Similarity: 26.6 20 N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 34 % A
% Cys: 0 0 0 0 0 34 0 0 9 0 0 0 9 0 0 % C
% Asp: 42 0 0 9 0 9 17 0 0 9 9 0 0 42 0 % D
% Glu: 0 0 0 0 0 9 0 0 17 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 9 9 0 0 9 0 0 0 0 25 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % G
% His: 0 9 0 0 34 0 0 9 0 0 9 0 0 0 9 % H
% Ile: 0 0 34 0 0 0 0 0 0 0 42 0 0 0 0 % I
% Lys: 0 0 9 0 9 17 0 17 0 42 9 42 0 0 0 % K
% Leu: 9 0 9 0 25 0 25 9 0 0 17 9 0 0 0 % L
% Met: 0 42 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 9 0 0 0 0 0 % N
% Pro: 0 0 0 17 0 9 0 0 0 9 0 17 25 0 0 % P
% Gln: 34 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 25 0 0 0 0 9 17 42 0 0 34 9 0 0 % R
% Ser: 0 0 9 25 0 0 0 0 9 9 0 0 42 17 42 % S
% Thr: 9 9 0 9 9 0 42 42 0 17 0 0 17 17 17 % T
% Val: 0 9 34 34 0 9 9 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _