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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCYT1B All Species: 20.91
Human Site: S322 Identified Species: 35.38
UniProt: Q9Y5K3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5K3 NP_001156737.1 369 41940 S322 S P K Q S P V S S P T R S R S
Chimpanzee Pan troglodytes XP_520980 351 40002 S304 S P K Q S P V S S P T R S R S
Rhesus Macaque Macaca mulatta XP_001090055 338 38695 L292 F I G N F L E L F G P D G A W
Dog Lupus familis XP_548900 369 41880 S322 S P K Q S P V S S P T R S R S
Cat Felis silvestris
Mouse Mus musculus Q811Q9 369 41882 S322 S P K Q S P V S S P T R S R S
Rat Rattus norvegicus Q9QZC4 369 41882 S322 S P K Q S P V S S P T R S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517894 294 33692 S248 I S P K Q S P S S S P T H E R
Chicken Gallus gallus XP_416793 493 54986 P446 A F S P R Q S P T S S P T R G
Frog Xenopus laevis NP_001089299 367 41920 Q318 L Q A I S P K Q S P S S S P T
Zebra Danio Brachydanio rerio NP_001076415 343 39443 S297 P R G S P S S S P P R D F S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395764 403 46370 R352 S P P A S P K R D G S P N G S
Nematode Worm Caenorhab. elegans P49583 362 41751 E315 E G S P T G I E H H L E T Q D
Sea Urchin Strong. purpuratus XP_001180754 425 48260 P338 S P P S S P R P G S P S A S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13259 424 49388 T361 E F T G E N S T A K S P D D N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 83.4 98.3 N.A. 98 98.6 N.A. 62.3 67.3 66.4 78.3 N.A. N.A. 45.9 37.6 45.1
Protein Similarity: 100 88.8 86.1 99.1 N.A. 99.4 99.4 N.A. 69.6 70.5 79.6 84.2 N.A. N.A. 57.3 51.7 60.4
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 13.3 6.6 33.3 13.3 N.A. N.A. 33.3 0 26.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 20 33.3 46.6 13.3 N.A. N.A. 46.6 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 0 0 8 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 15 8 8 8 % D
% Glu: 15 0 0 0 8 0 8 8 0 0 0 8 0 8 0 % E
% Phe: 8 15 0 0 8 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 8 15 8 0 8 0 0 8 15 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % H
% Ile: 8 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 36 8 0 0 15 0 0 8 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 8 0 8 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 8 % N
% Pro: 8 50 22 15 8 58 8 15 8 50 22 22 0 8 8 % P
% Gln: 0 8 0 36 8 8 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 0 8 0 8 8 0 0 8 36 0 43 8 % R
% Ser: 50 8 15 15 58 15 22 50 50 22 29 15 43 15 43 % S
% Thr: 0 0 8 0 8 0 0 8 8 0 36 8 15 0 8 % T
% Val: 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _