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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1B
All Species:
23.33
Human Site:
S335
Identified Species:
39.49
UniProt:
Q9Y5K3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K3
NP_001156737.1
369
41940
S335
R
S
P
S
R
S
P
S
P
T
F
S
W
L
P
Chimpanzee
Pan troglodytes
XP_520980
351
40002
S317
R
S
P
S
R
S
P
S
P
T
F
S
W
L
P
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
Q305
A
W
K
R
L
F
P
Q
P
A
T
S
A
S
I
Dog
Lupus familis
XP_548900
369
41880
S335
R
S
P
S
R
S
P
S
P
T
F
S
W
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q811Q9
369
41882
S335
R
S
P
S
R
S
P
S
P
T
F
S
W
L
P
Rat
Rattus norvegicus
Q9QZC4
369
41882
S335
R
S
P
S
R
S
P
S
P
T
F
S
W
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
F261
E
R
S
P
S
P
S
F
R
W
P
F
S
A
K
Chicken
Gallus gallus
XP_416793
493
54986
S459
R
G
R
S
P
S
R
S
P
S
P
P
W
V
F
Frog
Xenopus laevis
NP_001089299
367
41920
S331
P
T
R
E
R
S
P
S
P
S
F
R
W
P
F
Zebra Danio
Brachydanio rerio
NP_001076415
343
39443
P310
S
P
S
R
S
P
S
P
P
S
R
W
A
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395764
403
46370
D365
G
S
N
S
S
N
N
D
E
D
Q
T
S
P
P
Nematode Worm
Caenorhab. elegans
P49583
362
41751
E328
Q
D
E
E
E
E
E
E
A
L
E
E
E
K
V
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
D351
S
Y
W
D
I
E
D
D
V
D
Y
E
G
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
Q374
D
N
G
N
L
F
S
Q
E
D
D
E
D
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
83.4
98.3
N.A.
98
98.6
N.A.
62.3
67.3
66.4
78.3
N.A.
N.A.
45.9
37.6
45.1
Protein Similarity:
100
88.8
86.1
99.1
N.A.
99.4
99.4
N.A.
69.6
70.5
79.6
84.2
N.A.
N.A.
57.3
51.7
60.4
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
0
40
46.6
13.3
N.A.
N.A.
20
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
0
53.3
60
26.6
N.A.
N.A.
33.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
8
0
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
8
15
0
22
8
0
8
8
0
% D
% Glu:
8
0
8
15
8
15
8
8
15
0
8
22
8
0
0
% E
% Phe:
0
0
0
0
0
15
0
8
0
0
43
8
0
0
15
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
15
0
0
0
0
8
0
0
0
36
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
8
8
0
8
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
8
36
8
8
15
50
8
65
0
15
8
0
15
50
% P
% Gln:
8
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% Q
% Arg:
43
8
15
15
43
0
8
0
8
0
8
8
0
0
0
% R
% Ser:
15
43
15
50
22
50
22
50
0
22
0
43
15
8
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
36
8
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% V
% Trp:
0
8
8
0
0
0
0
0
0
8
0
8
50
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _