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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1B
All Species:
40.91
Human Site:
T197
Identified Species:
69.23
UniProt:
Q9Y5K3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K3
NP_001156737.1
369
41940
T197
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Chimpanzee
Pan troglodytes
XP_520980
351
40002
D194
I
I
T
R
I
C
R
D
Y
Q
V
F
A
T
V
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
Y182
S
A
G
S
D
D
V
Y
K
H
I
K
E
A
G
Dog
Lupus familis
XP_548900
369
41880
T197
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q811Q9
369
41882
T197
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Rat
Rattus norvegicus
Q9QZC4
369
41882
T197
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
R138
D
I
I
T
R
I
V
R
D
Y
D
V
Y
A
R
Chicken
Gallus gallus
XP_416793
493
54986
T323
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Frog
Xenopus laevis
NP_001089299
367
41920
T197
M
F
A
P
T
Q
R
T
E
G
I
S
T
S
D
Zebra Danio
Brachydanio rerio
NP_001076415
343
39443
Y187
I
T
R
I
V
R
D
Y
D
V
Y
A
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395764
403
46370
T234
M
F
V
A
T
Q
R
T
E
G
V
S
T
S
D
Nematode Worm
Caenorhab. elegans
P49583
362
41751
T201
M
F
L
E
T
E
R
T
E
G
V
S
T
S
D
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
T213
K
F
V
A
T
K
R
T
E
G
V
S
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
T224
K
F
L
T
T
Q
R
T
N
G
V
S
T
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
83.4
98.3
N.A.
98
98.6
N.A.
62.3
67.3
66.4
78.3
N.A.
N.A.
45.9
37.6
45.1
Protein Similarity:
100
88.8
86.1
99.1
N.A.
99.4
99.4
N.A.
69.6
70.5
79.6
84.2
N.A.
N.A.
57.3
51.7
60.4
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
100
93.3
0
N.A.
N.A.
86.6
73.3
73.3
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
20
100
93.3
33.3
N.A.
N.A.
93.3
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
15
0
0
0
0
0
0
0
8
8
15
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
8
8
15
0
8
0
0
0
72
% D
% Glu:
0
0
0
8
0
8
0
0
65
0
0
0
8
0
0
% E
% Phe:
0
72
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
72
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
15
15
8
8
8
8
0
0
0
0
50
0
0
0
0
% I
% Lys:
15
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
58
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
8
8
8
79
8
0
0
0
0
8
8
8
% R
% Ser:
8
0
0
8
0
0
0
0
0
0
0
72
0
72
0
% S
% Thr:
0
8
8
15
72
0
0
72
0
0
0
0
72
8
0
% T
% Val:
0
0
50
0
8
0
15
0
0
8
36
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
8
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _