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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1B
All Species:
36.36
Human Site:
Y225
Identified Species:
61.54
UniProt:
Q9Y5K3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K3
NP_001156737.1
369
41940
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Chimpanzee
Pan troglodytes
XP_520980
351
40002
Y222
S
L
A
N
M
K
R
Y
R
F
Q
N
Q
V
D
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
V210
S
D
I
I
T
R
I
V
R
D
Y
D
V
Y
A
Dog
Lupus familis
XP_548900
369
41880
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q811Q9
369
41882
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Rat
Rattus norvegicus
Q9QZC4
369
41882
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
K166
V
S
F
I
N
E
K
K
Y
H
L
Q
E
R
V
Chicken
Gallus gallus
XP_416793
493
54986
Y351
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Frog
Xenopus laevis
NP_001089299
367
41920
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Zebra Danio
Brachydanio rerio
NP_001076415
343
39443
R215
Y
I
N
E
K
K
Y
R
L
Q
N
Q
V
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395764
403
46370
Y262
R
R
N
L
A
R
G
Y
S
A
K
E
L
N
V
Nematode Worm
Caenorhab. elegans
P49583
362
41751
Y229
R
R
N
L
Q
R
G
Y
S
P
K
E
L
N
V
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
Y241
R
R
N
L
S
R
G
Y
S
A
R
D
L
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
A252
M
R
N
F
A
R
G
A
T
R
Q
E
L
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
83.4
98.3
N.A.
98
98.6
N.A.
62.3
67.3
66.4
78.3
N.A.
N.A.
45.9
37.6
45.1
Protein Similarity:
100
88.8
86.1
99.1
N.A.
99.4
99.4
N.A.
69.6
70.5
79.6
84.2
N.A.
N.A.
57.3
51.7
60.4
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
6.6
100
100
6.6
N.A.
N.A.
86.6
86.6
73.3
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
20
100
100
40
N.A.
N.A.
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
15
0
0
8
0
58
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
15
0
8
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
0
65
8
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
15
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
15
8
8
0
0
58
0
0
0
0
% K
% Leu:
0
8
0
65
0
0
0
0
8
0
8
0
72
0
0
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
79
8
8
0
0
0
0
0
8
8
0
72
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
0
0
8
15
15
8
0
0
% Q
% Arg:
65
72
0
0
0
79
8
8
15
8
8
0
0
8
8
% R
% Ser:
15
8
0
0
8
0
0
0
22
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
50
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
8
0
0
0
0
15
8
79
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
72
8
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _