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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1D
All Species:
21.21
Human Site:
S216
Identified Species:
33.33
UniProt:
Q9Y5K8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K8
NP_057078.1
247
28263
S216
K
K
I
L
K
E
K
S
E
K
D
L
E
Q
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537484
247
28262
S216
K
K
I
L
K
E
K
S
E
K
D
L
E
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
P57746
247
28351
F216
K
K
I
I
K
E
K
F
E
K
D
L
E
R
R
Rat
Rattus norvegicus
NP_955418
247
28290
S216
K
K
I
I
K
E
K
S
E
K
D
L
E
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505877
367
41306
T336
K
K
I
L
K
E
K
T
E
K
E
L
E
L
R
Chicken
Gallus gallus
XP_421199
247
28218
S216
K
K
V
L
K
E
K
S
E
K
E
R
E
L
R
Frog
Xenopus laevis
NP_001087010
248
28216
A216
K
K
I
I
K
D
K
A
E
K
E
R
A
K
W
Zebra Danio
Brachydanio rerio
NP_957254
248
28268
T216
K
K
Q
L
R
E
R
T
E
K
E
I
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7D2
246
27609
K219
A
R
I
K
A
D
A
K
K
A
E
L
L
Q
Q
Honey Bee
Apis mellifera
XP_394769
245
27448
L216
K
K
Q
A
K
A
K
L
E
A
A
R
A
E
M
Nematode Worm
Caenorhab. elegans
P34462
257
28768
A219
K
K
L
K
E
Q
E
A
A
Q
K
A
L
E
G
Sea Urchin
Strong. purpuratus
XP_786371
247
28130
E215
K
K
K
I
K
A
K
E
E
L
R
R
K
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XGM1
261
29040
V230
K
E
F
A
E
E
M
V
L
E
D
I
S
M
Q
Baker's Yeast
Sacchar. cerevisiae
P32610
256
29175
A228
M
K
L
K
R
D
R
A
E
Q
D
A
S
E
V
Red Bread Mold
Neurospora crassa
O59941
264
29474
A225
E
T
D
A
Q
M
K
A
K
K
A
E
Q
Q
R
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.5
N.A.
98.3
98.7
N.A.
64.5
95.5
89.5
87.5
N.A.
72.4
72.4
67.3
72
Protein Similarity:
100
N.A.
N.A.
100
N.A.
99.5
100
N.A.
65.9
97.1
95.1
94.3
N.A.
84.6
84.6
80.1
84.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
80
86.6
N.A.
80
73.3
46.6
46.6
N.A.
20
33.3
13.3
46.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
93.3
86.6
80
86.6
N.A.
53.3
40
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
51.9
51.8
Protein Similarity:
N.A.
N.A.
N.A.
70.5
71.4
69.7
P-Site Identity:
N.A.
N.A.
N.A.
20
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
20
7
14
7
27
7
14
14
14
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
20
0
0
0
0
40
0
0
0
0
% D
% Glu:
7
7
0
0
14
54
7
7
74
7
34
7
40
20
0
% E
% Phe:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
47
27
0
0
0
0
0
0
0
14
0
0
0
% I
% Lys:
80
80
7
20
60
0
67
7
14
60
7
0
7
14
0
% K
% Leu:
0
0
14
34
0
0
0
7
7
7
0
40
14
14
0
% L
% Met:
7
0
0
0
0
7
7
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
14
0
7
7
0
0
0
14
0
0
7
34
14
% Q
% Arg:
0
7
0
0
14
0
14
0
0
0
7
27
0
14
60
% R
% Ser:
0
0
0
0
0
0
0
27
0
0
0
0
14
0
0
% S
% Thr:
0
7
0
0
0
0
0
14
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _