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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNPO3 All Species: 33.94
Human Site: S404 Identified Species: 57.44
UniProt: Q9Y5L0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5L0 NP_036602.1 923 104203 S404 G E F R M R V S D L V K D L I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092805 909 102522 S404 G E F R M R V S D L V K D L I
Dog Lupus familis XP_857780 923 104203 S404 G E F R M R V S D L V K D L I
Cat Felis silvestris
Mouse Mus musculus Q6P2B1 923 104152 S404 G E F R M R V S D L V K D L I
Rat Rattus norvegicus Q9JM04 963 108169 Y433 D I S D T L M Y V Y E M L G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509710 913 103193 S394 G E F R M R V S D L V K D L I
Chicken Gallus gallus Q5ZIC8 958 107758 Y428 D I S D T L M Y V Y E M L G A
Frog Xenopus laevis NP_001087147 922 104164 S403 G E F R L R V S D L V K D L I
Zebra Danio Brachydanio rerio NP_957381 923 104218 S404 G E F R M R V S D L V K D V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608708 932 105736 S409 F D F R R K V S D L I K D V A
Honey Bee Apis mellifera XP_001121919 857 96229 F383 D S T E A A L F V M Q A V A K
Nematode Worm Caenorhab. elegans NP_494279 949 107038 S428 E S A L F V M S A V V Q N L L
Sea Urchin Strong. purpuratus XP_001181644 655 73805 E181 A F M E M M V E T P N Q A F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99189 972 110727 L415 R Y H M G D V L K D C T A V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 99.8 N.A. 99.3 23.6 N.A. 93.7 23.5 87.3 85.8 N.A. 42.4 41.5 29.2 31.3
Protein Similarity: 100 N.A. 98.2 100 N.A. 99.5 44.3 N.A. 96.4 43.9 94.1 94.2 N.A. 63.7 60.2 49.3 48.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 0 N.A. 100 0 93.3 93.3 N.A. 53.3 0 20 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 6.6 N.A. 100 6.6 100 100 N.A. 80 13.3 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 8 0 0 8 0 0 8 15 8 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 22 8 0 15 0 8 0 0 58 8 0 0 58 0 0 % D
% Glu: 8 50 0 15 0 0 0 8 0 0 15 0 0 0 0 % E
% Phe: 8 8 58 0 8 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 50 0 0 0 8 0 0 0 0 0 0 0 0 15 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 8 0 0 0 50 % I
% Lys: 0 0 0 0 0 8 0 0 8 0 0 58 0 0 8 % K
% Leu: 0 0 0 8 8 15 8 8 0 58 0 0 15 50 8 % L
% Met: 0 0 8 8 50 8 22 0 0 8 0 15 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 15 0 0 0 % Q
% Arg: 8 0 0 58 8 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 15 0 0 0 0 65 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 15 0 0 0 8 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 8 72 0 22 8 58 0 8 22 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 15 0 15 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _