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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNPO3 All Species: 23.03
Human Site: S597 Identified Species: 38.97
UniProt: Q9Y5L0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5L0 NP_036602.1 923 104203 S597 M A L K K L L S Q E P S N G I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092805 909 102522 S597 M A L K K L L S Q E P S N G I
Dog Lupus familis XP_857780 923 104203 S597 M A L K K L L S Q E P S N G I
Cat Felis silvestris
Mouse Mus musculus Q6P2B1 923 104152 S597 M A L K K L L S Q E P S N G I
Rat Rattus norvegicus Q9JM04 963 108169 E626 Q Q L E K L A E E I P K P S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509710 913 103193 S587 M A L K K L L S Q E P S N G I
Chicken Gallus gallus Q5ZIC8 958 107758 D621 Q Q L E K L A D E T P N P S N
Frog Xenopus laevis NP_001087147 922 104164 S596 N S L K K L L S Q D P N N G L
Zebra Danio Brachydanio rerio NP_957381 923 104218 A597 M A L K K L L A Q D S S S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608708 932 105736 D603 Q P L A Q L V D S T G S T P Q
Honey Bee Apis mellifera XP_001121919 857 96229 D571 H T D P P I E D S F E P H P C
Nematode Worm Caenorhab. elegans NP_494279 949 107038 S628 E G A P P R G S K A N E A W A
Sea Urchin Strong. purpuratus XP_001181644 655 73805 L369 I E K H P D Y L D P V L N F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99189 972 110727 P612 R Q I E A L I P Q W K A N P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 99.8 N.A. 99.3 23.6 N.A. 93.7 23.5 87.3 85.8 N.A. 42.4 41.5 29.2 31.3
Protein Similarity: 100 N.A. 98.2 100 N.A. 99.5 44.3 N.A. 96.4 43.9 94.1 94.2 N.A. 63.7 60.2 49.3 48.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 26.6 N.A. 100 26.6 66.6 66.6 N.A. 20 0 6.6 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 40 N.A. 100 46.6 93.3 86.6 N.A. 33.3 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 8 8 8 0 15 8 0 8 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 8 0 0 8 0 22 8 15 0 0 0 0 0 % D
% Glu: 8 8 0 22 0 0 8 8 15 36 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 0 8 0 0 0 0 8 0 0 0 8 0 0 50 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 8 0 0 8 8 0 0 8 0 0 0 0 36 % I
% Lys: 0 0 8 50 65 0 0 0 8 0 8 8 0 0 8 % K
% Leu: 0 0 72 0 0 79 50 8 0 0 0 8 0 0 15 % L
% Met: 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 8 15 58 0 15 % N
% Pro: 0 8 0 15 22 0 0 8 0 8 58 8 15 22 0 % P
% Gln: 22 22 0 0 8 0 0 0 58 0 0 0 0 0 8 % Q
% Arg: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 50 15 0 8 50 8 15 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 15 0 0 8 0 8 % T
% Val: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _