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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO3
All Species:
27.58
Human Site:
S605
Identified Species:
46.67
UniProt:
Q9Y5L0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5L0
NP_036602.1
923
104203
S605
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092805
909
102522
S605
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Dog
Lupus familis
XP_857780
923
104203
S605
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2B1
923
104152
S605
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Rat
Rattus norvegicus
Q9JM04
963
108169
K634
E
I
P
K
P
S
N
K
L
A
I
V
H
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509710
913
103193
S595
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Chicken
Gallus gallus
Q5ZIC8
958
107758
K629
E
T
P
N
P
S
N
K
L
A
I
I
H
I
L
Frog
Xenopus laevis
NP_001087147
922
104164
S604
Q
D
P
N
N
G
L
S
S
D
P
T
L
F
L
Zebra Danio
Brachydanio rerio
NP_957381
923
104218
S605
Q
D
S
S
S
G
K
S
S
D
P
T
V
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608708
932
105736
K611
S
T
G
S
T
P
Q
K
G
E
R
T
D
P
V
Honey Bee
Apis mellifera
XP_001121919
857
96229
Q579
S
F
E
P
H
P
C
Q
S
A
V
T
E
M
W
Nematode Worm
Caenorhab. elegans
NP_494279
949
107038
S636
K
A
N
E
A
W
A
S
L
A
T
R
P
M
L
Sea Urchin
Strong. purpuratus
XP_001181644
655
73805
M377
D
P
V
L
N
F
L
M
T
G
L
R
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99189
972
110727
L620
Q
W
K
A
N
P
T
L
L
A
P
Q
I
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
99.8
N.A.
99.3
23.6
N.A.
93.7
23.5
87.3
85.8
N.A.
42.4
41.5
29.2
31.3
Protein Similarity:
100
N.A.
98.2
100
N.A.
99.5
44.3
N.A.
96.4
43.9
94.1
94.2
N.A.
63.7
60.2
49.3
48.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
13.3
73.3
66.6
N.A.
13.3
13.3
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
100
26.6
100
86.6
N.A.
26.6
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
8
0
0
36
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
0
50
0
0
15
0
8
% D
% Glu:
15
36
8
8
0
0
0
0
0
8
0
0
8
8
8
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
0
0
43
0
% F
% Gly:
0
0
8
0
0
50
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
8
0
0
0
0
36
0
0
0
15
8
8
15
0
% I
% Lys:
8
0
8
8
0
0
8
22
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
15
8
29
0
8
0
8
0
72
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
15
0
% M
% Asn:
0
0
8
15
58
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
58
8
15
22
0
0
0
0
58
0
8
8
0
% P
% Gln:
58
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
15
0
0
0
% R
% Ser:
15
0
8
50
8
15
0
58
58
0
0
0
0
0
0
% S
% Thr:
0
15
0
0
8
0
8
0
8
0
8
65
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
8
8
43
0
8
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _