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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO3
All Species:
21.82
Human Site:
S74
Identified Species:
36.92
UniProt:
Q9Y5L0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5L0
NP_036602.1
923
104203
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
T
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092805
909
102522
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
T
D
Dog
Lupus familis
XP_857780
923
104203
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2B1
923
104152
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
T
D
Rat
Rattus norvegicus
Q9JM04
963
108169
Y89
L
H
I
K
I
S
R
Y
W
S
D
I
P
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509710
913
103193
D78
D
S
H
A
S
L
R
D
S
L
L
S
H
I
Q
Chicken
Gallus gallus
Q5ZIC8
958
107758
T84
C
T
S
R
S
P
A
T
G
T
T
S
L
P
D
Frog
Xenopus laevis
NP_001087147
922
104164
F74
K
M
K
I
Q
T
S
F
Y
E
L
P
S
D
S
Zebra Danio
Brachydanio rerio
NP_957381
923
104218
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608708
932
105736
H79
S
F
S
E
L
P
P
H
T
H
E
S
L
R
D
Honey Bee
Apis mellifera
XP_001121919
857
96229
K69
A
A
Q
T
M
R
T
K
I
Q
L
C
F
Q
E
Nematode Worm
Caenorhab. elegans
NP_494279
949
107038
L93
W
N
N
W
I
F
E
L
L
N
Q
C
Q
A
L
Sea Urchin
Strong. purpuratus
XP_001181644
655
73805
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99189
972
110727
D76
L
R
N
K
V
T
Y
D
L
S
Q
L
E
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
99.8
N.A.
99.3
23.6
N.A.
93.7
23.5
87.3
85.8
N.A.
42.4
41.5
29.2
31.3
Protein Similarity:
100
N.A.
98.2
100
N.A.
99.5
44.3
N.A.
96.4
43.9
94.1
94.2
N.A.
63.7
60.2
49.3
48.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
33.3
N.A.
0
6.6
0
93.3
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
66.6
N.A.
0
20
13.3
93.3
N.A.
33.3
26.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
15
0
0
8
0
0
8
58
% D
% Glu:
0
0
0
8
0
0
8
0
0
8
43
0
8
0
8
% E
% Phe:
0
8
0
0
0
8
0
8
36
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
8
50
0
0
0
8
0
0
8
0
8
0
% I
% Lys:
8
36
8
50
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
15
0
0
0
8
8
0
8
15
8
22
43
15
0
8
% L
% Met:
36
8
36
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
15
0
0
0
0
0
0
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
15
8
0
0
0
0
8
43
15
0
% P
% Gln:
0
0
8
0
8
36
0
0
0
8
15
0
8
8
8
% Q
% Arg:
0
8
0
8
0
8
15
0
0
0
0
0
0
8
0
% R
% Ser:
8
8
15
0
15
8
8
36
8
15
0
22
8
0
8
% S
% Thr:
0
8
0
8
0
15
43
8
8
8
8
0
0
36
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
8
36
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _