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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO3
All Species:
24.24
Human Site:
T237
Identified Species:
41.03
UniProt:
Q9Y5L0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5L0
NP_036602.1
923
104203
T237
E
V
L
Q
Q
D
K
T
S
S
N
L
H
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092805
909
102522
T237
E
V
L
Q
Q
D
K
T
S
S
N
L
H
E
A
Dog
Lupus familis
XP_857780
923
104203
T237
E
V
L
Q
Q
D
K
T
S
S
N
L
H
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2B1
923
104152
T237
E
V
L
Q
Q
D
K
T
S
S
N
L
H
E
A
Rat
Rattus norvegicus
Q9JM04
963
108169
L250
I
Q
A
A
F
A
A
L
Q
D
S
E
L
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509710
913
103193
A235
S
S
N
L
H
E
A
A
S
D
C
V
C
S
A
Chicken
Gallus gallus
Q5ZIC8
958
107758
L245
I
Q
A
A
F
T
S
L
Q
D
P
E
L
F
D
Frog
Xenopus laevis
NP_001087147
922
104164
T236
Q
V
L
Q
Q
D
Q
T
P
T
N
L
H
E
A
Zebra Danio
Brachydanio rerio
NP_957381
923
104218
T237
Q
V
L
Q
R
D
E
T
S
T
N
L
H
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608708
932
105736
H242
P
E
T
S
G
K
L
H
D
N
A
T
E
C
V
Honey Bee
Apis mellifera
XP_001121919
857
96229
T226
T
S
D
V
I
V
Y
T
L
Q
I
L
G
N
H
Nematode Worm
Caenorhab. elegans
NP_494279
949
107038
S271
I
F
V
E
M
V
E
S
F
Y
V
Q
I
V
N
Sea Urchin
Strong. purpuratus
XP_001181644
655
73805
D24
T
V
L
P
E
E
V
D
S
H
S
L
R
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99189
972
110727
A245
G
N
E
S
D
M
E
A
F
D
S
A
I
D
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
99.8
N.A.
99.3
23.6
N.A.
93.7
23.5
87.3
85.8
N.A.
42.4
41.5
29.2
31.3
Protein Similarity:
100
N.A.
98.2
100
N.A.
99.5
44.3
N.A.
96.4
43.9
94.1
94.2
N.A.
63.7
60.2
49.3
48.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
13.3
0
73.3
73.3
N.A.
0
13.3
0
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
26.6
0
93.3
100
N.A.
6.6
13.3
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
15
0
8
15
15
0
0
8
8
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
8
% C
% Asp:
0
0
8
0
8
43
0
8
8
29
0
0
0
8
15
% D
% Glu:
29
8
8
8
8
15
22
0
0
0
0
15
8
43
0
% E
% Phe:
0
8
0
0
15
0
0
0
15
0
0
0
0
15
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
8
0
0
8
0
8
0
0
43
0
8
% H
% Ile:
22
0
0
0
8
0
0
0
0
0
8
0
15
0
0
% I
% Lys:
0
0
0
0
0
8
29
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
50
8
0
0
8
15
8
0
0
58
15
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
8
43
0
0
8
8
% N
% Pro:
8
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
15
15
0
43
36
0
8
0
15
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
15
0
15
0
0
8
8
50
29
22
0
0
8
0
% S
% Thr:
15
0
8
0
0
8
0
50
0
15
0
8
0
0
0
% T
% Val:
0
50
8
8
0
15
8
0
0
0
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _