KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO3
All Species:
26.97
Human Site:
T458
Identified Species:
45.64
UniProt:
Q9Y5L0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5L0
NP_036602.1
923
104203
T458
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092805
909
102522
T458
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Dog
Lupus familis
XP_857780
923
104203
T458
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2B1
923
104152
T458
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Rat
Rattus norvegicus
Q9JM04
963
108169
V487
I
D
V
N
Y
S
D
V
V
P
G
L
I
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509710
913
103193
T448
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Chicken
Gallus gallus
Q5ZIC8
958
107758
V482
I
D
V
N
Y
S
D
V
V
P
G
L
I
G
L
Frog
Xenopus laevis
NP_001087147
922
104164
T457
I
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Zebra Danio
Brachydanio rerio
NP_957381
923
104218
T458
V
D
P
E
N
N
P
T
L
M
E
V
L
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608708
932
105736
V463
I
L
P
D
E
N
E
V
I
P
K
V
V
E
A
Honey Bee
Apis mellifera
XP_001121919
857
96229
R437
C
E
W
I
D
N
H
R
Q
S
L
E
P
V
L
Nematode Worm
Caenorhab. elegans
NP_494279
949
107038
L482
F
E
Q
H
S
N
L
L
E
P
V
V
R
W
T
Sea Urchin
Strong. purpuratus
XP_001181644
655
73805
R235
R
E
L
T
D
L
Y
R
P
Y
I
E
R
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99189
972
110727
I469
I
S
L
T
E
N
T
I
L
P
E
I
I
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
99.8
N.A.
99.3
23.6
N.A.
93.7
23.5
87.3
85.8
N.A.
42.4
41.5
29.2
31.3
Protein Similarity:
100
N.A.
98.2
100
N.A.
99.5
44.3
N.A.
96.4
43.9
94.1
94.2
N.A.
63.7
60.2
49.3
48.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
100
6.6
93.3
86.6
N.A.
26.6
6.6
13.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
100
40
100
93.3
N.A.
60
20
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
65
0
8
15
0
15
0
0
0
0
0
0
0
0
% D
% Glu:
0
22
0
50
15
0
8
0
8
0
58
15
0
58
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
0
0
15
43
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
36
0
0
8
0
0
0
8
8
0
8
8
22
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
0
8
15
0
0
8
8
8
58
0
8
15
50
8
22
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
15
50
79
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
58
0
0
0
50
0
8
36
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
15
0
0
0
0
15
0
0
% R
% Ser:
0
8
0
0
8
15
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
8
50
0
0
0
0
0
0
8
% T
% Val:
43
0
15
0
0
0
0
22
15
43
8
65
8
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
15
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _