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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPRB
All Species:
5.15
Human Site:
S123
Identified Species:
9.44
UniProt:
Q9Y5M8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5M8
NP_067026.2
271
29702
S123
I
D
L
P
G
H
E
S
L
R
L
Q
F
L
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853477
271
29822
S123
I
D
L
P
G
H
E
S
L
R
L
Q
F
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P47758
269
29560
F124
P
G
H
E
S
L
R
F
Q
L
L
D
R
F
K
Rat
Rattus norvegicus
Q4FZX7
269
29550
L124
P
G
H
E
S
L
R
L
Q
F
L
D
R
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520821
187
20738
R46
F
W
R
F
I
R
S
R
K
T
G
K
N
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080846
264
29170
E123
S
L
R
H
Q
F
L
E
Q
Y
K
A
S
A
R
Zebra Danio
Brachydanio rerio
NP_001002572
266
29462
Q123
G
H
E
S
L
R
T
Q
I
V
E
K
Y
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788485
244
27070
Y103
L
V
D
I
P
G
H
Y
R
V
R
D
K
C
L
Honey Bee
Apis mellifera
XP_393949
244
27722
Y103
P
G
H
E
R
L
R
Y
K
F
F
D
Q
F
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195524
262
28693
N121
R
Q
R
I
Q
F
W
N
R
F
K
T
Q
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131722
256
28274
H115
H
I
V
D
V
P
G
H
A
R
L
K
P
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196186
260
29057
H119
H
L
V
D
V
P
G
H
S
R
L
R
P
K
L
Baker's Yeast
Sacchar. cerevisiae
P36057
244
26956
K103
Y
K
L
S
D
Y
L
K
T
R
A
K
F
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.9
N.A.
90.4
90.7
N.A.
47.5
N.A.
63.4
56.4
N.A.
33.9
36.9
N.A.
43.5
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
94
94.8
N.A.
53.8
N.A.
80
71.2
N.A.
56.4
59.7
N.A.
64.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
6.6
6.6
N.A.
0
N.A.
0
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
13.3
13.3
N.A.
6.6
N.A.
0
26.6
N.A.
6.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
31.3
N.A.
31.7
23.2
N.A.
Protein Similarity:
N.A.
50.5
N.A.
50.9
41.3
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
8
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
16
8
16
8
0
0
0
0
0
0
31
0
0
8
% D
% Glu:
0
0
8
24
0
0
16
8
0
0
8
0
0
0
16
% E
% Phe:
8
0
0
8
0
16
0
8
0
24
8
0
24
24
0
% F
% Gly:
8
24
0
0
16
8
16
0
0
0
8
0
0
0
0
% G
% His:
16
8
24
8
0
16
8
16
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
16
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
16
0
16
31
8
24
31
% K
% Leu:
8
16
24
0
8
24
16
8
16
8
47
0
0
16
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
24
0
0
16
8
16
0
0
0
0
0
0
16
0
0
% P
% Gln:
0
8
0
0
16
0
0
8
24
0
0
16
16
0
0
% Q
% Arg:
8
0
24
0
8
16
24
8
16
39
8
8
16
0
16
% R
% Ser:
8
0
0
16
16
0
8
16
8
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
8
0
8
0
0
0
% T
% Val:
0
8
16
0
16
0
0
0
0
16
0
0
0
8
8
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
16
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _