KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPRB
All Species:
4.55
Human Site:
S219
Identified Species:
8.33
UniProt:
Q9Y5M8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5M8
NP_067026.2
271
29702
S219
P
S
T
L
D
S
S
S
T
A
P
A
Q
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853477
271
29822
S219
P
S
T
L
D
S
S
S
T
A
P
A
Q
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P47758
269
29560
P220
L
D
S
S
S
T
A
P
A
Q
L
G
K
K
G
Rat
Rattus norvegicus
Q4FZX7
269
29550
P220
L
D
S
S
S
T
A
P
A
Q
L
G
K
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520821
187
20738
A142
Q
R
E
V
K
D
V
A
E
F
L
Y
Q
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080846
264
29170
G219
N
S
G
V
A
Q
L
G
K
K
G
K
D
F
D
Zebra Danio
Brachydanio rerio
NP_001002572
266
29462
V219
D
G
A
V
G
G
S
V
Y
L
G
K
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788485
244
27070
G199
Q
S
V
G
D
E
D
G
S
K
S
I
T
L
G
Honey Bee
Apis mellifera
XP_393949
244
27722
L199
A
S
A
T
N
I
F
L
G
K
Q
E
K
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195524
262
28693
L217
S
G
D
A
N
T
F
L
G
K
Q
G
K
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131722
256
28274
D211
I
S
S
A
D
I
S
D
E
V
Q
L
G
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196186
260
29057
N215
V
S
T
A
D
I
A
N
D
F
T
I
G
I
E
Baker's Yeast
Sacchar. cerevisiae
P36057
244
26956
A199
K
I
N
E
E
D
Y
A
E
N
T
L
D
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.9
N.A.
90.4
90.7
N.A.
47.5
N.A.
63.4
56.4
N.A.
33.9
36.9
N.A.
43.5
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
94
94.8
N.A.
53.8
N.A.
80
71.2
N.A.
56.4
59.7
N.A.
64.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
26.6
6.6
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
33.3
33.3
N.A.
26.6
N.A.
13.3
20
N.A.
33.3
20
N.A.
20
Percent
Protein Identity:
N.A.
31.3
N.A.
31.7
23.2
N.A.
Protein Similarity:
N.A.
50.5
N.A.
50.9
41.3
N.A.
P-Site Identity:
N.A.
20
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
24
8
0
24
16
16
16
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
8
0
39
16
8
8
8
0
0
0
16
16
8
% D
% Glu:
0
0
8
8
8
8
0
0
24
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
16
0
0
16
0
0
0
8
16
% F
% Gly:
0
16
8
8
8
8
0
16
16
0
16
24
16
8
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
24
0
0
0
0
0
16
0
8
0
% I
% Lys:
8
0
0
0
8
0
0
0
8
31
0
16
39
16
8
% K
% Leu:
16
0
0
16
0
0
8
16
0
8
24
16
0
24
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
16
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
16
0
0
0
0
0
0
16
0
0
16
0
0
0
8
% P
% Gln:
16
0
0
0
0
8
0
0
0
16
24
0
24
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
54
24
16
16
16
31
16
8
0
8
0
0
0
0
% S
% Thr:
0
0
24
8
0
24
0
0
16
0
16
0
8
0
0
% T
% Val:
8
0
8
24
0
0
8
8
0
8
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _