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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPRB
All Species:
7.58
Human Site:
S235
Identified Species:
13.89
UniProt:
Q9Y5M8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5M8
NP_067026.2
271
29702
S235
K
G
K
E
F
E
F
S
Q
L
P
L
K
V
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853477
271
29822
S235
K
G
K
E
F
E
F
S
Q
L
P
L
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P47758
269
29560
P236
E
F
E
F
S
Q
L
P
L
K
V
E
F
L
E
Rat
Rattus norvegicus
Q4FZX7
269
29550
P236
E
F
E
F
S
Q
L
P
L
K
V
E
F
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520821
187
20738
V158
D
S
L
V
L
K
N
V
P
S
L
L
I
A
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080846
264
29170
K235
T
Q
L
P
M
K
V
K
F
L
E
C
S
T
H
Zebra Danio
Brachydanio rerio
NP_001002572
266
29462
N235
F
E
F
S
Q
L
A
N
R
V
E
F
I
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788485
244
27070
S215
P
G
R
D
F
E
F
S
H
I
A
Q
N
I
Q
Honey Bee
Apis mellifera
XP_393949
244
27722
I215
F
S
H
L
D
I
N
I
E
F
A
E
C
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195524
262
28693
V233
F
S
H
L
A
N
P
V
D
F
V
E
C
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131722
256
28274
C227
E
A
F
N
F
S
Q
C
Q
N
K
V
A
V
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196186
260
29057
C231
E
V
F
S
F
T
H
C
S
N
K
V
T
V
A
Baker's Yeast
Sacchar. cerevisiae
P36057
244
26956
A215
S
T
D
G
F
K
F
A
N
L
E
A
S
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.9
N.A.
90.4
90.7
N.A.
47.5
N.A.
63.4
56.4
N.A.
33.9
36.9
N.A.
43.5
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
94
94.8
N.A.
53.8
N.A.
80
71.2
N.A.
56.4
59.7
N.A.
64.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
0
N.A.
33.3
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
33.3
33.3
N.A.
13.3
N.A.
13.3
20
N.A.
66.6
6.6
N.A.
0
Percent
Protein Identity:
N.A.
31.3
N.A.
31.7
23.2
N.A.
Protein Similarity:
N.A.
50.5
N.A.
50.9
41.3
N.A.
P-Site Identity:
N.A.
20
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
8
0
0
16
8
8
8
31
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
8
16
0
16
% C
% Asp:
8
0
8
8
8
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
31
8
16
16
0
24
0
0
8
0
24
31
0
8
31
% E
% Phe:
24
16
24
16
47
0
31
0
8
16
0
8
16
0
0
% F
% Gly:
0
24
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
0
0
8
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
8
0
8
0
0
16
8
0
% I
% Lys:
16
0
16
0
0
24
0
8
0
16
16
0
16
0
0
% K
% Leu:
0
0
16
16
8
8
16
0
16
31
8
24
0
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
16
8
8
16
0
0
8
0
0
% N
% Pro:
8
0
0
8
0
0
8
16
8
0
16
0
0
0
0
% P
% Gln:
0
8
0
0
8
16
8
0
24
0
0
8
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
24
0
16
16
8
0
24
8
8
0
0
16
16
0
% S
% Thr:
8
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% T
% Val:
0
8
0
8
0
0
8
16
0
8
24
16
0
39
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _