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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPRB
All Species:
7.27
Human Site:
S257
Identified Species:
13.33
UniProt:
Q9Y5M8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5M8
NP_067026.2
271
29702
S257
G
G
R
G
D
V
G
S
A
D
I
Q
D
L
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853477
271
29822
S257
G
G
R
G
D
T
G
S
A
D
I
Q
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P47758
269
29560
I258
G
D
T
G
S
A
D
I
Q
D
L
E
K
W
L
Rat
Rattus norvegicus
Q4FZX7
269
29550
V258
G
D
A
G
S
A
D
V
Q
D
L
E
K
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520821
187
20738
Q180
A
K
S
A
K
I
I
Q
Q
Q
L
E
K
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080846
264
29170
E257
D
A
N
I
S
N
V
E
G
W
L
A
K
L
V
Zebra Danio
Brachydanio rerio
NP_001002572
266
29462
D257
E
D
G
D
A
D
I
D
A
L
E
K
C
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788485
244
27070
T237
D
T
E
L
D
P
L
T
D
W
L
A
R
L
L
Honey Bee
Apis mellifera
XP_393949
244
27722
N237
S
A
D
M
E
Q
L
N
N
W
L
K
K
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195524
262
28693
T255
E
G
E
L
N
T
V
T
E
W
I
S
N
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131722
256
28274
F249
N
V
L
A
V
E
Q
F
I
R
E
H
V
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196186
260
29057
F253
E
T
I
Q
I
E
D
F
I
R
E
Y
I
K
P
Baker's Yeast
Sacchar. cerevisiae
P36057
244
26956
R237
K
R
K
I
S
Q
W
R
E
W
I
D
E
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.9
N.A.
90.4
90.7
N.A.
47.5
N.A.
63.4
56.4
N.A.
33.9
36.9
N.A.
43.5
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
94
94.8
N.A.
53.8
N.A.
80
71.2
N.A.
56.4
59.7
N.A.
64.9
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
20
20
N.A.
0
N.A.
6.6
13.3
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
33.3
33.3
N.A.
20
N.A.
13.3
20
N.A.
26.6
33.3
N.A.
40
Percent
Protein Identity:
N.A.
31.3
N.A.
31.7
23.2
N.A.
Protein Similarity:
N.A.
50.5
N.A.
50.9
41.3
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
16
8
16
0
0
24
0
0
16
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
16
24
8
8
24
8
24
8
8
31
0
8
16
0
0
% D
% Glu:
24
0
16
0
8
16
0
8
16
0
24
24
8
8
16
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
31
24
8
31
0
0
16
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
16
8
8
16
8
16
0
31
0
8
8
8
% I
% Lys:
8
8
8
0
8
0
0
0
0
0
0
16
39
16
0
% K
% Leu:
0
0
8
16
0
0
16
0
0
8
47
0
0
47
39
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
8
0
8
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
16
8
8
24
8
0
16
0
0
0
% Q
% Arg:
0
8
16
0
0
0
0
8
0
16
0
0
8
8
0
% R
% Ser:
8
0
8
0
31
0
0
16
0
0
0
8
0
0
0
% S
% Thr:
0
16
8
0
0
16
0
16
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
8
16
8
0
0
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
8
0
0
39
0
0
0
16
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _