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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPRB All Species: 5.15
Human Site: Y103 Identified Species: 9.44
UniProt: Q9Y5M8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5M8 NP_067026.2 271 29702 Y103 I T D S C A V Y R V N N N R G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853477 271 29822 Y103 I T D S S A M Y R V N N T R A
Cat Felis silvestris
Mouse Mus musculus P47758 269 29560 N104 S S A I Y K V N N N R G N S L
Rat Rattus norvegicus Q4FZX7 269 29550 N104 S S A I Y K V N N N R G N S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520821 187 20738 K26 G G I T V T Y K A A C C G L I
Chicken Gallus gallus
Frog Xenopus laevis NP_001080846 264 29170 G103 Y K V K S D K G T S L T L V D
Zebra Danio Brachydanio rerio NP_001002572 266 29462 S103 S A T Y K S K S E R G N S W T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788485 244 27070 N83 T F T S I K E N V G D Y R T G
Honey Bee Apis mellifera XP_393949 244 27722 I83 V K E N I G D I I I N N R S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195524 262 28693 S101 Y Q V T G Q R S M L L E V V D
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131722 256 28274 H95 N S D T F V L H S E Q E R K G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196186 260 29057 H99 N E G T F V L H S E N T K K G
Baker's Yeast Sacchar. cerevisiae P36057 244 26956 V83 A D Y D G S G V T L V D F P G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 92.9 N.A. 90.4 90.7 N.A. 47.5 N.A. 63.4 56.4 N.A. 33.9 36.9 N.A. 43.5
Protein Similarity: 100 N.A. N.A. 95.5 N.A. 94 94.8 N.A. 53.8 N.A. 80 71.2 N.A. 56.4 59.7 N.A. 64.9
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 13.3 13.3 N.A. 0 N.A. 0 6.6 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 N.A. N.A. 80 N.A. 20 20 N.A. 6.6 N.A. 0 20 N.A. 20 40 N.A. 13.3
Percent
Protein Identity: N.A. 31.3 N.A. 31.7 23.2 N.A.
Protein Similarity: N.A. 50.5 N.A. 50.9 41.3 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 46.6 N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 0 0 16 0 0 8 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 0 8 24 8 0 8 8 0 0 0 8 8 0 0 16 % D
% Glu: 0 8 8 0 0 0 8 0 8 16 0 16 0 0 0 % E
% Phe: 0 8 0 0 16 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 8 8 0 16 8 8 8 0 8 8 16 8 0 39 % G
% His: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % H
% Ile: 16 0 8 16 16 0 0 8 8 8 0 0 0 0 8 % I
% Lys: 0 16 0 8 8 24 16 8 0 0 0 0 8 16 0 % K
% Leu: 0 0 0 0 0 0 16 0 0 16 16 0 8 8 24 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 16 0 0 8 0 0 0 24 16 16 31 31 24 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 16 8 16 0 24 16 0 % R
% Ser: 24 24 0 24 16 16 0 16 16 8 0 0 8 24 0 % S
% Thr: 8 16 16 31 0 8 0 0 16 0 0 16 8 8 8 % T
% Val: 8 0 16 0 8 16 24 8 8 16 8 0 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 16 0 8 8 16 0 8 16 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _