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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH3
All Species:
13.03
Human Site:
S181
Identified Species:
31.85
UniProt:
Q9Y5N1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5N1
NP_009163.2
445
48671
S181
W
E
Y
L
S
G
G
S
S
I
P
E
G
H
C
Chimpanzee
Pan troglodytes
Q9N2A7
440
48835
M176
F
Y
L
P
V
I
I
M
T
V
L
Y
W
H
I
Rhesus Macaque
Macaca mulatta
P56489
460
51414
R171
W
Q
Y
L
V
G
E
R
T
V
L
A
G
Q
C
Dog
Lupus familis
XP_855189
392
43503
I147
F
Y
N
W
Y
F
L
I
T
A
S
T
L
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P58406
445
48523
S181
W
E
Y
L
S
G
G
S
S
I
P
E
G
H
C
Rat
Rattus norvegicus
Q9QYN8
445
48570
S181
W
E
Y
L
S
G
G
S
S
I
P
E
G
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505994
495
55199
R218
D
R
F
L
S
V
T
R
A
V
T
Y
R
A
Q
Chicken
Gallus gallus
P30372
466
51547
R172
W
Q
F
I
V
G
G
R
T
V
P
D
K
D
C
Frog
Xenopus laevis
P30544
484
54107
R179
W
Q
F
I
V
G
Q
R
T
V
P
S
G
E
C
Zebra Danio
Brachydanio rerio
NP_001020689
473
53488
S211
W
E
H
I
T
G
G
S
V
V
P
D
G
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.2
31.2
78.1
N.A.
94.3
93.9
N.A.
67.2
25.7
26.6
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.7
49.7
81.5
N.A.
95.9
95.7
N.A.
74.1
47.8
47.9
63.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
40
0
N.A.
100
100
N.A.
13.3
33.3
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
60
13.3
N.A.
100
100
N.A.
33.3
73.3
66.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
20
0
10
0
% D
% Glu:
0
40
0
0
0
0
10
0
0
0
0
30
0
30
0
% E
% Phe:
20
0
30
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
70
50
0
0
0
0
0
60
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
40
0
% H
% Ile:
0
0
0
30
0
10
10
10
0
30
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
10
50
0
0
10
0
0
0
20
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
60
0
0
0
0
% P
% Gln:
0
30
0
0
0
0
10
0
0
0
0
0
0
10
10
% Q
% Arg:
0
10
0
0
0
0
0
40
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
40
0
0
40
30
0
10
10
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
0
50
0
10
10
0
0
0
% T
% Val:
0
0
0
0
40
10
0
0
10
60
0
0
0
0
0
% V
% Trp:
70
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
20
40
0
10
0
0
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _