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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC6L All Species: 48.48
Human Site: S72 Identified Species: 76.19
UniProt: Q9Y5N6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5N6 NP_055136.1 252 28107 S72 R A Y L I K L S G L N K E T Y
Chimpanzee Pan troglodytes XP_001161833 252 28124 S72 R A Y L I K L S G L N K E T Y
Rhesus Macaque Macaca mulatta XP_001113625 252 28130 S72 R A Y L I K L S G L N K K T Y
Dog Lupus familis XP_539609 252 27646 S72 R A Y L I K L S G L N K K M Y
Cat Felis silvestris
Mouse Mus musculus Q9WUJ8 262 29170 S72 R A Y L I R L S G L N K M M Y
Rat Rattus norvegicus NP_001028862 262 28796 S72 R A Y L I K L S G L N K K M Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521050 272 30470 S92 R T D L V K L S G L N K K A Y
Chicken Gallus gallus XP_414114 301 33273 S105 K N S F V K L S G L N R T A Y
Frog Xenopus laevis NP_001086912 225 24746 S72 K D Y L V R L S G L N K K V Y
Zebra Danio Brachydanio rerio NP_997836 256 28612 S71 K E Y A I K L S G L N P K V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y1B2 257 29221 S72 K E Q A L K L S G L R K S Q Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793313 204 22972 V61 V Q F G C V G V V E H A N L V
Poplar Tree Populus trichocarpa XP_002316713 285 32005 S70 R Q A A I R L S G M S E K A Y
Maize Zea mays NP_001151122 293 32508 S70 R A E A V R M S G M S E K A Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVH3 284 31751 S70 R Q A A V K L S G M S E K A Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 84.1 N.A. 74.4 70.6 N.A. 66.5 48.5 51.5 51.9 N.A. 26.4 N.A. N.A. 28.5
Protein Similarity: 100 99.2 98.8 90.8 N.A. 85.5 80.1 N.A. 74.6 61.7 65.8 71.4 N.A. 47 N.A. N.A. 45.6
P-Site Identity: 100 100 93.3 86.6 N.A. 80 86.6 N.A. 66.6 46.6 60 60 N.A. 46.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. 80 66.6 86.6 73.3 N.A. 60 N.A. N.A. 13.3
Percent
Protein Identity: 27.3 26.6 N.A. 25.3 N.A. N.A.
Protein Similarity: 47.3 47.4 N.A. 46.4 N.A. N.A.
P-Site Identity: 40 33.3 N.A. 40 N.A. N.A.
P-Site Similarity: 73.3 80 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 47 14 34 0 0 0 0 0 0 0 7 0 34 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 14 7 0 0 0 0 0 0 7 0 20 14 0 0 % E
% Phe: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 7 0 94 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 54 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 27 0 0 0 0 67 0 0 0 0 0 60 60 0 0 % K
% Leu: 0 0 0 54 7 0 87 0 0 74 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 7 0 0 20 0 0 7 20 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 67 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 20 7 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 67 0 0 0 0 27 0 0 0 0 7 7 0 0 0 % R
% Ser: 0 0 7 0 0 0 0 94 0 0 20 0 7 0 0 % S
% Thr: 0 7 0 0 0 0 0 0 0 0 0 0 7 20 0 % T
% Val: 7 0 0 0 34 7 0 7 7 0 0 0 0 14 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 54 0 0 0 0 0 0 0 0 0 0 0 94 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _