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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC6L All Species: 20.61
Human Site: T195 Identified Species: 32.38
UniProt: Q9Y5N6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5N6 NP_055136.1 252 28107 T195 R E P G D V A T P P R K R K K
Chimpanzee Pan troglodytes XP_001161833 252 28124 T195 R E P G D V A T P P R K R K K
Rhesus Macaque Macaca mulatta XP_001113625 252 28130 A195 R E P G D L A A P P R K K K K
Dog Lupus familis XP_539609 252 27646 T195 R E A G D S A T P P K K K K K
Cat Felis silvestris
Mouse Mus musculus Q9WUJ8 262 29170 R195 R D S A D L A R P A L K R K K
Rat Rattus norvegicus NP_001028862 262 28796 S195 R D S A D L A S P A L K K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521050 272 30470 S215 I D H N Q S D S P P P K R Q K
Chicken Gallus gallus XP_414114 301 33273 A228 K D D I P L A A E T S E T L Q
Frog Xenopus laevis NP_001086912 225 24746 K181 R L S I Q L E K I G L Q L C Q
Zebra Danio Brachydanio rerio NP_997836 256 28612 S189 Q E I C N E A S S L E K P V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y1B2 257 29221 S194 K E S K V P S S T D M E G K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793313 204 22972 G167 L K R S F E D G V S P P K Q S
Poplar Tree Populus trichocarpa XP_002316713 285 32005 D211 K G N R E L L D V L P E K R K
Maize Zea mays NP_001151122 293 32508 P212 R E L L D V L P S K R K H E D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVH3 284 31751 S229 Y S S G D E S S C Y K R H K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 84.1 N.A. 74.4 70.6 N.A. 66.5 48.5 51.5 51.9 N.A. 26.4 N.A. N.A. 28.5
Protein Similarity: 100 99.2 98.8 90.8 N.A. 85.5 80.1 N.A. 74.6 61.7 65.8 71.4 N.A. 47 N.A. N.A. 45.6
P-Site Identity: 100 100 80 73.3 N.A. 53.3 46.6 N.A. 33.3 6.6 6.6 26.6 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 66.6 73.3 N.A. 53.3 40 26.6 46.6 N.A. 40 N.A. N.A. 20
Percent
Protein Identity: 27.3 26.6 N.A. 25.3 N.A. N.A.
Protein Similarity: 47.3 47.4 N.A. 46.4 N.A. N.A.
P-Site Identity: 6.6 40 N.A. 26.6 N.A. N.A.
P-Site Similarity: 46.6 46.6 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 14 0 0 54 14 0 14 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 7 0 0 0 0 7 0 % C
% Asp: 0 27 7 0 54 0 14 7 0 7 0 0 0 0 7 % D
% Glu: 0 47 0 0 7 20 7 0 7 0 7 20 0 7 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 34 0 0 0 7 0 7 0 0 7 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 14 0 0 % H
% Ile: 7 0 7 14 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 20 7 0 7 0 0 0 7 0 7 14 60 34 54 67 % K
% Leu: 7 7 7 7 0 40 14 0 0 14 20 0 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 7 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 0 7 7 0 7 47 34 20 7 7 0 0 % P
% Gln: 7 0 0 0 14 0 0 0 0 0 0 7 0 14 14 % Q
% Arg: 54 0 7 7 0 0 0 7 0 0 27 7 27 7 0 % R
% Ser: 0 7 34 7 0 14 14 34 14 7 7 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 20 7 7 0 0 7 0 0 % T
% Val: 0 0 0 0 7 20 0 0 14 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _