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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMPPB
All Species:
46.06
Human Site:
S132
Identified Species:
63.33
UniProt:
Q9Y5P6
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5P6
NP_037466.2
360
39834
S132
R
H
H
G
Q
E
G
S
I
L
V
T
K
V
E
Chimpanzee
Pan troglodytes
XP_001165804
387
42605
S132
R
H
H
G
Q
E
G
S
I
L
V
T
K
V
E
Rhesus Macaque
Macaca mulatta
XP_001106890
360
39913
S132
R
H
H
G
Q
E
G
S
I
L
V
T
K
V
E
Dog
Lupus familis
XP_850642
876
95988
S132
R
H
H
G
Q
E
G
S
I
L
V
T
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ7
360
39898
S132
R
H
H
G
Q
E
G
S
I
L
V
T
K
V
E
Rat
Rattus norvegicus
Q5XIC1
420
46173
L140
Q
R
H
P
F
L
L
L
G
T
T
A
N
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414268
439
48772
S211
R
Q
H
G
G
E
G
S
I
V
V
T
R
V
E
Frog
Xenopus laevis
Q68EY9
360
40133
T132
K
H
H
G
K
E
G
T
I
V
V
T
K
V
E
Zebra Danio
Brachydanio rerio
Q6DBU5
360
40125
T132
Q
Q
H
G
R
E
G
T
I
V
V
T
K
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JZB4
369
40430
G141
H
C
N
H
G
K
E
G
T
I
V
V
T
K
V
Honey Bee
Apis mellifera
XP_392845
359
39840
G131
H
K
S
H
G
K
E
G
T
I
I
V
T
K
V
Nematode Worm
Caenorhab. elegans
A3QMC8
365
40081
T131
K
N
H
G
K
E
G
T
I
A
V
T
K
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316262
361
39591
S133
K
V
H
G
G
E
A
S
I
M
V
T
K
V
D
Maize
Zea mays
NP_001142302
361
39566
T133
K
S
H
G
G
E
A
T
I
M
V
T
K
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181507
361
39559
S133
K
S
H
G
G
E
A
S
I
M
V
T
K
V
D
Baker's Yeast
Sacchar. cerevisiae
P41940
361
39547
I133
A
H
G
G
K
G
T
I
V
A
T
K
V
D
E
Red Bread Mold
Neurospora crassa
Q7RVR8
364
40035
I133
A
H
G
D
E
G
T
I
V
V
T
K
V
E
E
Conservation
Percent
Protein Identity:
100
92.7
99.1
39.8
N.A.
98
33.8
N.A.
N.A.
61.5
82.2
81.1
N.A.
68.5
66.3
63
N.A.
Protein Similarity:
100
93
99.4
40.7
N.A.
99.1
48.5
N.A.
N.A.
71.5
92.2
93.3
N.A.
84.2
83.6
76.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
73.3
73.3
66.6
N.A.
6.6
0
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
86.6
100
93.3
N.A.
26.6
20
93.3
N.A.
Percent
Protein Identity:
61.2
61.7
N.A.
61.7
57.8
59.6
Protein Similarity:
79.5
79.5
N.A.
79.5
77
79.1
P-Site Identity:
60
53.3
N.A.
60
20
13.3
P-Site Similarity:
80
80
N.A.
80
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
18
0
0
12
0
6
0
0
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
0
0
0
0
0
0
6
18
% D
% Glu:
0
0
0
0
6
71
12
0
0
0
0
0
0
6
65
% E
% Phe:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
77
36
12
53
12
6
0
0
0
0
0
0
% G
% His:
12
48
77
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
71
12
6
0
0
0
0
% I
% Lys:
30
6
0
0
18
12
0
0
0
0
0
12
65
12
0
% K
% Leu:
0
0
0
0
0
6
6
6
0
30
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
18
0
0
0
0
0
% M
% Asn:
0
6
6
0
0
0
0
0
0
0
0
0
6
0
0
% N
% Pro:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
0
0
30
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
36
6
0
0
6
0
0
0
0
0
0
0
6
6
0
% R
% Ser:
0
12
6
0
0
0
0
48
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
24
12
6
18
71
12
0
6
% T
% Val:
0
6
0
0
0
0
0
0
12
24
77
12
12
71
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _