KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMPPB
All Species:
37.27
Human Site:
S246
Identified Species:
51.25
UniProt:
Q9Y5P6
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5P6
NP_037466.2
360
39834
S246
K
Q
P
E
R
L
C
S
G
P
G
I
V
G
N
Chimpanzee
Pan troglodytes
XP_001165804
387
42605
S246
K
Q
P
E
R
L
C
S
G
P
G
I
V
G
N
Rhesus Macaque
Macaca mulatta
XP_001106890
360
39913
S246
K
H
P
E
R
L
Y
S
G
P
G
I
V
G
N
Dog
Lupus familis
XP_850642
876
95988
S246
K
Q
P
E
Q
L
C
S
G
P
G
I
V
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ7
360
39898
S246
K
H
P
E
R
L
Y
S
G
P
G
I
V
G
N
Rat
Rattus norvegicus
Q5XIC1
420
46173
G279
R
L
A
R
H
T
A
G
G
P
R
I
R
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414268
439
48772
S325
Q
H
P
E
K
L
H
S
G
P
G
V
V
G
N
Frog
Xenopus laevis
Q68EY9
360
40133
A246
K
H
P
E
W
L
H
A
G
P
G
F
I
G
N
Zebra Danio
Brachydanio rerio
Q6DBU5
360
40125
A246
Q
A
P
E
R
L
R
A
G
P
G
F
L
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JZB4
369
40430
T255
K
Q
S
P
K
L
Y
T
G
P
G
V
V
G
N
Honey Bee
Apis mellifera
XP_392845
359
39840
S245
K
S
P
A
K
L
Y
S
G
P
G
V
V
G
N
Nematode Worm
Caenorhab. elegans
A3QMC8
365
40081
T245
T
K
S
D
K
L
E
T
G
S
N
I
H
P
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316262
361
39591
N247
N
S
S
S
K
L
A
N
G
P
H
I
V
G
N
Maize
Zea mays
NP_001142302
361
39566
A247
K
S
A
A
R
L
A
A
G
A
H
V
V
G
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181507
361
39559
S247
K
S
P
A
K
L
T
S
G
P
H
I
V
G
N
Baker's Yeast
Sacchar. cerevisiae
P41940
361
39547
T247
R
Q
P
K
K
L
A
T
G
A
N
I
V
G
N
Red Bread Mold
Neurospora crassa
Q7RVR8
364
40035
L250
K
E
L
A
P
T
T
L
P
Y
I
H
G
G
N
Conservation
Percent
Protein Identity:
100
92.7
99.1
39.8
N.A.
98
33.8
N.A.
N.A.
61.5
82.2
81.1
N.A.
68.5
66.3
63
N.A.
Protein Similarity:
100
93
99.4
40.7
N.A.
99.1
48.5
N.A.
N.A.
71.5
92.2
93.3
N.A.
84.2
83.6
76.7
N.A.
P-Site Identity:
100
100
86.6
93.3
N.A.
86.6
33.3
N.A.
N.A.
66.6
60
60
N.A.
60
66.6
20
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
86.6
40
N.A.
N.A.
86.6
73.3
80
N.A.
80
80
46.6
N.A.
Percent
Protein Identity:
61.2
61.7
N.A.
61.7
57.8
59.6
Protein Similarity:
79.5
79.5
N.A.
79.5
77
79.1
P-Site Identity:
46.6
46.6
N.A.
66.6
53.3
20
P-Site Similarity:
60
60
N.A.
73.3
80
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
12
24
0
0
24
18
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
18
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
6
0
48
0
0
6
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
6
95
0
59
0
6
95
0
% G
% His:
0
24
0
0
6
0
12
0
0
0
18
6
6
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
6
59
6
0
0
% I
% Lys:
65
6
0
6
42
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
6
6
0
0
89
0
6
0
0
0
0
6
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
6
0
0
12
0
0
0
95
% N
% Pro:
0
0
65
6
6
0
0
0
6
77
0
0
0
6
0
% P
% Gln:
12
30
0
0
6
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
6
36
0
6
0
0
0
6
0
6
0
0
% R
% Ser:
0
24
18
6
0
0
0
48
0
6
0
0
0
0
0
% S
% Thr:
6
0
0
0
0
12
12
18
0
0
0
0
0
0
6
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
24
71
0
0
% V
% Trp:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
24
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _