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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMPPB
All Species:
47.58
Human Site:
T136
Identified Species:
65.42
UniProt:
Q9Y5P6
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5P6
NP_037466.2
360
39834
T136
Q
E
G
S
I
L
V
T
K
V
E
E
P
S
K
Chimpanzee
Pan troglodytes
XP_001165804
387
42605
T136
Q
E
G
S
I
L
V
T
K
V
E
E
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001106890
360
39913
T136
Q
E
G
S
I
L
V
T
K
V
E
E
P
S
K
Dog
Lupus familis
XP_850642
876
95988
T136
Q
E
G
S
I
L
V
T
K
V
E
E
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ7
360
39898
T136
Q
E
G
S
I
L
V
T
K
V
E
E
P
S
K
Rat
Rattus norvegicus
Q5XIC1
420
46173
A144
F
L
L
L
G
T
T
A
N
R
T
Q
S
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414268
439
48772
T215
G
E
G
S
I
V
V
T
R
V
E
E
P
A
K
Frog
Xenopus laevis
Q68EY9
360
40133
T136
K
E
G
T
I
V
V
T
K
V
E
E
P
S
K
Zebra Danio
Brachydanio rerio
Q6DBU5
360
40125
T136
R
E
G
T
I
V
V
T
K
V
E
E
P
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JZB4
369
40430
V145
G
K
E
G
T
I
V
V
T
K
V
E
E
P
S
Honey Bee
Apis mellifera
XP_392845
359
39840
V135
G
K
E
G
T
I
I
V
T
K
V
E
E
P
S
Nematode Worm
Caenorhab. elegans
A3QMC8
365
40081
T135
K
E
G
T
I
A
V
T
K
V
E
E
P
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316262
361
39591
T137
G
E
A
S
I
M
V
T
K
V
D
E
P
S
K
Maize
Zea mays
NP_001142302
361
39566
T137
G
E
A
T
I
M
V
T
K
V
D
E
P
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181507
361
39559
T137
G
E
A
S
I
M
V
T
K
V
D
E
P
S
K
Baker's Yeast
Sacchar. cerevisiae
P41940
361
39547
K137
K
G
T
I
V
A
T
K
V
D
E
P
S
K
Y
Red Bread Mold
Neurospora crassa
Q7RVR8
364
40035
K137
E
G
T
I
V
V
T
K
V
E
E
P
S
K
Y
Conservation
Percent
Protein Identity:
100
92.7
99.1
39.8
N.A.
98
33.8
N.A.
N.A.
61.5
82.2
81.1
N.A.
68.5
66.3
63
N.A.
Protein Similarity:
100
93
99.4
40.7
N.A.
99.1
48.5
N.A.
N.A.
71.5
92.2
93.3
N.A.
84.2
83.6
76.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
73.3
80
80
N.A.
13.3
6.6
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
100
100
N.A.
26.6
26.6
93.3
N.A.
Percent
Protein Identity:
61.2
61.7
N.A.
61.7
57.8
59.6
Protein Similarity:
79.5
79.5
N.A.
79.5
77
79.1
P-Site Identity:
73.3
66.6
N.A.
73.3
6.6
6.6
P-Site Similarity:
86.6
86.6
N.A.
86.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
0
0
12
0
6
0
0
0
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
6
18
0
0
0
0
% D
% Glu:
6
71
12
0
0
0
0
0
0
6
65
83
12
0
0
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
36
12
53
12
6
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
71
12
6
0
0
0
0
0
0
0
0
% I
% Lys:
18
12
0
0
0
0
0
12
65
12
0
0
0
12
71
% K
% Leu:
0
6
6
6
0
30
0
0
0
0
0
0
0
6
0
% L
% Met:
0
0
0
0
0
18
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
71
12
0
% P
% Gln:
30
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
6
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% R
% Ser:
0
0
0
48
0
0
0
0
0
0
0
0
18
65
12
% S
% Thr:
0
0
12
24
12
6
18
71
12
0
6
0
0
0
0
% T
% Val:
0
0
0
0
12
24
77
12
12
71
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _