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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R3B
All Species:
2.12
Human Site:
T121
Identified Species:
4.67
UniProt:
Q9Y5P8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5P8
NP_037371.2
575
65061
T121
E
E
P
L
P
P
A
T
S
Q
S
I
P
T
F
Chimpanzee
Pan troglodytes
XP_001153482
1150
130149
L705
N
N
V
V
N
A
P
L
S
I
N
I
P
R
F
Rhesus Macaque
Macaca mulatta
XP_001115107
1150
130076
L705
N
N
V
V
N
A
P
L
S
I
N
I
P
R
F
Dog
Lupus familis
XP_848247
567
63710
A115
E
Q
P
L
P
P
A
A
S
Q
N
I
P
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z176
491
55687
Y71
G
H
T
V
P
A
F
Y
F
P
C
G
R
P
P
Rat
Rattus norvegicus
Q6AXZ3
453
53360
L34
L
K
D
E
E
M
D
L
F
T
K
Y
Y
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505856
619
70306
T107
S
E
K
L
T
S
L
T
F
A
T
G
L
N
F
Chicken
Gallus gallus
XP_416866
581
67390
L129
E
E
T
L
P
P
S
L
S
Q
T
I
P
T
F
Frog
Xenopus laevis
NP_001082625
565
65249
L118
E
E
P
L
T
P
A
L
S
Q
N
I
P
K
F
Zebra Danio
Brachydanio rerio
Q803V3
457
53314
F38
K
A
E
E
S
E
L
F
S
K
Y
Y
T
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396366
1240
138144
R758
Q
R
H
V
K
A
N
R
N
V
H
I
P
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.1
31.5
81.7
N.A.
54
21.2
N.A.
56
75
64.5
22.4
N.A.
N.A.
27.8
N.A.
N.A.
Protein Similarity:
100
40
40
88.1
N.A.
63.6
38.9
N.A.
66.2
85.1
75.8
40
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
100
26.6
26.6
73.3
N.A.
6.6
0
N.A.
26.6
73.3
73.3
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
40
40
86.6
N.A.
13.3
13.3
N.A.
33.3
86.6
80
26.6
N.A.
N.A.
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
37
28
10
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
37
37
10
19
10
10
0
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
10
10
28
0
0
0
0
0
73
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
19
0
64
0
0
0
% I
% Lys:
10
10
10
0
10
0
0
0
0
10
10
0
0
10
0
% K
% Leu:
10
0
0
46
0
0
19
46
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
19
0
0
19
0
10
0
10
0
37
0
0
10
0
% N
% Pro:
0
0
28
0
37
37
19
0
0
10
0
0
64
10
10
% P
% Gln:
10
10
0
0
0
0
0
0
0
37
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
10
28
0
% R
% Ser:
10
0
0
0
10
10
10
0
64
0
10
0
0
10
0
% S
% Thr:
0
0
19
0
19
0
0
19
0
10
19
0
10
19
0
% T
% Val:
0
0
19
37
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
19
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _