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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C5
All Species:
22.73
Human Site:
S274
Identified Species:
45.45
UniProt:
Q9Y5Q8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q8
NP_001116295.1
519
59571
S274
N
A
V
K
A
N
I
S
V
H
P
D
K
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103027
528
60386
S283
N
A
V
K
A
N
I
S
V
H
P
D
K
L
K
Dog
Lupus familis
XP_537807
520
59982
S278
N
A
V
K
A
N
I
S
V
H
P
D
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2T8
520
60483
S274
N
A
V
K
S
N
V
S
V
H
P
D
K
L
K
Rat
Rattus norvegicus
NP_001073410
515
59893
S274
N
A
V
K
S
N
V
S
V
H
P
D
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511625
516
59384
S276
N
A
V
K
A
N
I
S
V
H
P
D
K
L
K
Chicken
Gallus gallus
NP_001025855
324
36635
R93
R
V
K
R
R
S
R
R
K
R
L
G
E
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693575
529
60525
D293
N
A
V
K
A
N
I
D
I
H
P
E
K
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609947
480
55616
A249
C
P
I
W
T
R
I
A
L
Q
Y
E
S
G
L
Honey Bee
Apis mellifera
XP_001122915
497
58075
E265
F
V
D
F
S
T
P
E
V
P
S
K
A
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309715
515
59755
K247
R
L
L
D
K
N
L
K
F
T
Y
Q
T
L
K
Maize
Zea mays
NP_001131401
555
62739
H274
R
F
L
D
D
N
V
H
V
S
Q
N
Q
F
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
87.3
N.A.
85.1
83.8
N.A.
82.6
45.6
N.A.
53.5
N.A.
27.9
31.6
N.A.
N.A.
Protein Similarity:
100
N.A.
97.7
93.8
N.A.
92.3
90.7
N.A.
90.5
53.9
N.A.
73.1
N.A.
48.3
48.7
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
100
0
N.A.
73.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
20
N.A.
93.3
N.A.
33.3
13.3
N.A.
N.A.
Percent
Protein Identity:
23.1
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
43.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
42
0
0
9
0
0
0
0
9
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
17
9
0
0
9
0
0
0
50
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
17
9
0
0
% E
% Phe:
9
9
0
9
0
0
0
0
9
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
59
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
50
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
59
9
0
0
9
9
0
0
9
59
0
75
% K
% Leu:
0
9
17
0
0
0
9
0
9
0
9
0
0
59
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
59
0
0
0
0
75
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
0
0
0
9
0
0
9
59
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
9
9
9
0
% Q
% Arg:
25
0
0
9
9
9
9
9
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
25
9
0
50
0
9
9
0
9
0
0
% S
% Thr:
0
0
0
0
9
9
0
0
0
9
0
0
9
0
0
% T
% Val:
0
17
59
0
0
0
25
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _