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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF3C5 All Species: 15.45
Human Site: S383 Identified Species: 30.91
UniProt: Q9Y5Q8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Q8 NP_001116295.1 519 59571 S383 S G A R K P A S S K Y K L K D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103027 528 60386 S392 S G A R K P A S S K Y K L K D
Dog Lupus familis XP_537807 520 59982 S387 A S S R K S N S N K Y K L K D
Cat Felis silvestris
Mouse Mus musculus Q8R2T8 520 60483 Y383 D G P R K L T Y N K Y K L K D
Rat Rattus norvegicus NP_001073410 515 59893 Y383 D G P R K L T Y N K Y K L K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511625 516 59384 K385 A K K S V S S K Y K L K D S I
Chicken Gallus gallus NP_001025855 324 36635 S202 A E N L I G L S R A R R P N N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693575 529 60525 L402 P V T A K Y M L K E S I Y I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609947 480 55616 R358 E H K L P R S R Q C M L R Y C
Honey Bee Apis mellifera XP_001122915 497 58075 R374 T S T V K C K R N Y S E Y T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309715 515 59755 C356 K P S K Q T S C I Y E T G W L
Maize Zea mays NP_001131401 555 62739 R383 S Y Q S V C S R S T G W F S K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.3 87.3 N.A. 85.1 83.8 N.A. 82.6 45.6 N.A. 53.5 N.A. 27.9 31.6 N.A. N.A.
Protein Similarity: 100 N.A. 97.7 93.8 N.A. 92.3 90.7 N.A. 90.5 53.9 N.A. 73.1 N.A. 48.3 48.7 N.A. N.A.
P-Site Identity: 100 N.A. 100 60 N.A. 60 60 N.A. 13.3 6.6 N.A. 6.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 80 N.A. 66.6 66.6 N.A. 26.6 26.6 N.A. 13.3 N.A. 6.6 26.6 N.A. N.A.
Percent
Protein Identity: 23.1 24.8 N.A. N.A. N.A. N.A.
Protein Similarity: 44.8 43.2 N.A. N.A. N.A. N.A.
P-Site Identity: 0 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 17 9 0 0 17 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 17 0 9 0 9 0 0 0 0 9 % C
% Asp: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 42 % D
% Glu: 9 9 0 0 0 0 0 0 0 9 9 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % F
% Gly: 0 34 0 0 0 9 0 0 0 0 9 0 9 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 9 0 0 9 0 9 9 % I
% Lys: 9 9 17 9 59 0 9 9 9 50 0 50 0 42 9 % K
% Leu: 0 0 0 17 0 17 9 9 0 0 9 9 42 0 17 % L
% Met: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 9 0 34 0 0 0 0 9 9 % N
% Pro: 9 9 17 0 9 17 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 9 0 9 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 42 0 9 0 25 9 0 9 9 9 0 0 % R
% Ser: 25 17 17 17 0 17 34 34 25 0 17 0 0 17 0 % S
% Thr: 9 0 17 0 0 9 17 0 0 9 0 9 0 9 0 % T
% Val: 0 9 0 9 17 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % W
% Tyr: 0 9 0 0 0 9 0 17 9 17 42 0 17 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _