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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF3C5 All Species: 22.73
Human Site: Y167 Identified Species: 45.45
UniProt: Q9Y5Q8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Q8 NP_001116295.1 519 59571 Y167 F H Q E L P L Y I P P P I F S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103027 528 60386 Y176 F H Q E L P L Y I P P P I F S
Dog Lupus familis XP_537807 520 59982 Y171 F H Q E L P L Y I P P P I F S
Cat Felis silvestris
Mouse Mus musculus Q8R2T8 520 60483 Y167 F H Q E L P L Y I P P P I F S
Rat Rattus norvegicus NP_001073410 515 59893 Y167 F H Q E L P L Y I P P P I F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511625 516 59384 Y169 F N Q E L P L Y I P P P I F S
Chicken Gallus gallus NP_001025855 324 36635
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693575 529 60525 I186 D N P V P L F I P P P I F S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609947 480 55616 L158 K R R H S Q L L A L P E L F T
Honey Bee Apis mellifera XP_001122915 497 58075 L179 E L P E L Q I L G R V E T E F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309715 515 59755 P156 P D D V M M L P P P L F S L K
Maize Zea mays NP_001131401 555 62739 K186 S V K D R P T K I A L V P S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.3 87.3 N.A. 85.1 83.8 N.A. 82.6 45.6 N.A. 53.5 N.A. 27.9 31.6 N.A. N.A.
Protein Similarity: 100 N.A. 97.7 93.8 N.A. 92.3 90.7 N.A. 90.5 53.9 N.A. 73.1 N.A. 48.3 48.7 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 0 N.A. 13.3 N.A. 20 13.3 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 0 N.A. 20 N.A. 40 20 N.A. N.A.
Percent
Protein Identity: 23.1 24.8 N.A. N.A. N.A. N.A.
Protein Similarity: 44.8 43.2 N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 59 0 0 0 0 0 0 0 17 0 9 0 % E
% Phe: 50 0 0 0 0 0 9 0 0 0 0 9 9 59 9 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 42 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 9 59 0 0 9 50 0 0 % I
% Lys: 9 0 9 0 0 0 0 9 0 0 0 0 0 0 9 % K
% Leu: 0 9 0 0 59 9 67 17 0 9 17 0 9 9 0 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 17 0 9 59 0 9 17 67 67 50 9 0 0 % P
% Gln: 0 0 50 0 0 17 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 9 0 9 0 0 0 0 9 0 0 0 0 9 % R
% Ser: 9 0 0 0 9 0 0 0 0 0 0 0 9 17 59 % S
% Thr: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 9 % T
% Val: 0 9 0 17 0 0 0 0 0 0 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _